Tag Archives: Vitamin D

Vitamin D Levels In Pregnancy Linked with Child IQ – Study

Vitamin D is a critical nutrient and has many important functions in the body. A mother’s vitamin D supply is passed to her baby in utero and helps regulate processes including brain development. A study published today in The Journal of Nutrition showed that mothers’ vitamin D levels during pregnancy were associated with their children’s IQ, suggesting that higher vitamin D levels in pregnancy may lead to greater childhood IQ scores. The study also identified significantly lower levels of vitamin D levels among Black pregnant women.

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Melissa Melough, the lead author of the study and research scientist in the Department of Child Health, Behavior, and Development at Seattle Children’s Research Institute, says vitamin D deficiency is common among the general population as well as pregnant women, but notes that Black women are at greater risk. Melough says she hopes the study will help health care providers address disparities among women of color and those who are at higher risk for vitamin D deficiency.

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Blood Vitamin D levels can predict future health risks and death

Free, circulating Vitamin D levels in the blood may be a better predictor of future health risks in aging men, according to a study being presented at e-ECE 2020. These data suggest the free, precursor form of vitamin D found circulating in the bloodstream is a more accurate predictor of future health and disease risk, than the often measured total Vitamin D. Since Vitamin D deficiency is associated with multiple serious health conditions as we get older, this study suggests that further investigation into Vitamin D levels and their link to poor health may be a promising area for further research.

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Vitamin D deficiency is common in Europe, especially in elderly people. It has been associated with a higher risk for developing many aging-related diseases, such as cardiovascular disease, cancer and osteoporosis. However, there are several forms, or metabolites, of Vitamin D in the body but it is the total amount of these metabolites that is most often used to assess the Vitamin D status of people. The prohormone, 25-dihydroxyvitamin D is converted to 1,25-dihydroxyvitamin D, which is considered the active form of vitamin D in our body. More than 99% of all Vitamin D metabolites in our blood are bound to proteins, so only a very small fraction is free to be biologically active. Therefore the free, active forms may be a better predictor of current and future health.

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Vitamin D: How much is too much of a good thing? – Study

When bare skin is exposed to sunlight, it makes Vitamin D, which is needed by our bodies to absorb calcium and ensure strong, healthy bones. With bathing suit skin exposure, it only takes about 10-15 minutes of sun exposure during the summer to generate all the vitamin D your body needs for the day.  Exposure to sunlight is diminished during the long winter months. This results in many turning to supplements to get the required vitamin D, according to the University of Calgary.

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For normal, healthy adults, Health Canada recommends a total daily intake of 600 international units (IU) up to age 70, and 800 IU after age 70. Other sources, like Osteoporosis Canada, suggest adults at risk of osteoporosis, a condition characterized by bone loss, should take 400 – 2,000 IU of Vitamin D. However, some people may be taking up to 20 times the recommended daily dose to prevent or treat a variety of medical conditions that might be related to having not enough vitamin D. So, what is the correct dose? And, how much is too much? Continue reading

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Does sunscreen compromise vitamin D levels?

I am somewhat paranoid about my bike riding in the sun as I have had three skin cancer operations. Foolishly, because I am Italian and tan don’t burn, I never felt the need for sunscreen. Not one of my best decisions. As my dermatologist said, “There is no such thing as a healthy tan.” I now lather up big time before riding in the sun.

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Here is the sun rising over Lake Michigan on a morning ride.

Sunscreen can reduce the sun’s adverse effects, but there are concerns that it might inhibit the body’s production of vitamin D. In a new British Journal of Dermatology study, however, investigators recorded an increase of vitamin D in participants during a week of cloudless weather, with very high UV index, even when sunscreens were used properly and prevented sunburn.

Sunlight contains UVA and UVB radiation, and the latter is essential for vitamin D synthesis. Two sunscreens with the same SPF were compared. Sunscreen with a high UVA protection factor enabled significantly higher vitamin D synthesis than a low UVA protection factor sunscreen, likely because it allows more UVB transmission.

The findings indicate that the benefits of sunscreen use can be obtained without compromising vitamin D levels.

“Sunlight is the main source of vitamin D. Sunscreens can prevent sunburn and skin cancer, but there has been a lot of uncertainty about the effects of sunscreens on vitamin D,” said lead author Prof. Antony Young, of King’s College London. “Our study, during a week of perfect weather in Tenerife, showed that sunscreens, even when used optimally to prevent sunburn, allowed excellent vitamin D synthesis.”

You can read more about skin cancer in general and my three skin cancers here.

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Study shows magnesium optimizes vitamin D status

I don’t know a lot about vitamin D except that our body manufactures that we can get too much of it.

A randomized trial by Vanderbilt-Ingram Cancer Center researchers indicates that magnesium optimizes vitamin D status, raising it in people with deficient levels and lowering it in people with high levels.

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The study reported in the December issue of The American Journal of Clinical Nutrition is important because of controversial findings from ongoing research into the association of vitamin D levels with colorectal cancer and other diseases, including a recent report from the VITAL trial. It gave confirmation to a prior observational study in 2013 by the researchers that linked low magnesium levels with low vitamin D levels.

The trial also revealed something new — that magnesium had a regulating effect in people with high vitamin D levels. The research provides the first evidence that magnesium may play an important role in optimizing vitamin D levels and preventing conditions related to vitamin D levels. Continue reading

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What You Need to Know for May – National Skin Cancer Awareness Month

May is National Skin Cancer Awareness Month. Makes sense. We should be coming into some sunny days right now. (Unless you live in Chicago as I do where we still have March temps).

In order to get through the coming sunny days herewith a list of links of all the items I have filed on skin cancer and sunburn since the blog began in 2010. This includes my own bout with skin cancer in 2012.

Looking at your face in the mirror, things that change in size, shape or color can be skin cancer.

Remember the words my dermatologist told me, “There’s no such thing as a healthy tan.”

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Myths and facts about sunburn and sunscreen

Vitamin D and Your Body – Harvard

How to protect yourself from sunburn and skin cancer

Do I have skin cancer?

What did I learn after being diagnosed with skin cancer?

What happened during my skin cancer surgery?

What about exercise after surgery?

Important facts about skin cancer?

What to do about extreme heat

Tony

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Low Magnesium Levels Make Vitamin D Ineffective – Study

​A study in The Journal of the American Osteopathic Association Suggests Up to 50 Percent of U.S. Population is Magnesium Deficient

There is a caveat to the push for increased Vitamin D: Don’t forget magnesium.

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A review published in The Journal of the American Osteopathic Association found Vitamin D can’t be metabolized without sufficient magnesium levels, meaning Vitamin D remains stored and inactive for as many as 50 percent of Americans.

“People are taking Vitamin D supplements but don’t realize how it gets metabolized. Without magnesium, Vitamin D is not really useful or safe,” says study co-author Mohammed S. Razzaque, MBBS, PhD, a professor of pathology at Lake Erie College of Osteopathic Medicine.

Razzaque explains that consumption of Vitamin D supplements can increase a person’s calcium and phosphate levels even if they remain Vitamin D deficient. The problem is people may suffer from vascular calcification if their magnesium levels aren’t high enough to prevent the complication.

Patients with optimum magnesium levels require less Vitamin D supplementation to achieve sufficient Vitamin D levels. Magnesium also reduces osteoporosis, helping to mitigate the risk of bone fracture that can be attributed to low levels of Vitamin D, Razzaque noted.

Deficiency in either of these nutrients is reported to be associated with various disorders, including skeletal deformities, cardiovascular diseases, and metabolic syndrome.

While the recommended daily allowance for magnesium is 420 mg for males and 320 mg for females, the standard diet in the United States contains only about 50 percent of that amount. As much as half of the total population is estimated to be consuming a magnesium-deficient diet.

Researchers say the magnesium consumption from natural foods has decreased in the past few decades, owing to industrialized agriculture and changes in dietary habits. Magnesium status is low in populations who consume processed foods that are high in refined grains, fat, phosphate, and sugar.

“By consuming an optimal amount of magnesium, one may be able to lower the risks of Vitamin D deficiency, and reduce the dependency on Vitamin D supplements,” says Razzaque.

Magnesium is the fourth most abundant mineral in the human body after calcium, potassium, and sodium. Foods high in magnesium include almonds, bananas, beans, broccoli, brown rice, cashews, egg yolk, fish oil, flaxseed, green vegetables, milk, mushrooms, other nuts, oatmeal, pumpkin seeds, sesame seeds, soybeans, sunflower seeds, sweet corn, tofu, and whole grains.

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Some rheumatoid arthritis cells respond to Vitamin D – MNT

I have written numerous times about the arthritis problems in my thumbs. I suffer from osteoarthritis.This is the most common for of arthritis. Rheumatoid arthritis, however, is also a painful, if less common, affliction. Osteoarthritis (OA) is the most common type of arthritis. On the other hand, rheumatoid arthritis (RA) is recognized as the most crippling or disabling type of arthritis.

After studying immune cells taken from the joints of people with rheumatoid arthritis, scientists have found that once the disease sets in, some types of cell lose their sensitivity to vitamin D, according to Medical News Today.

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The team — which comprised researchers from University College London and the University of Birmingham, both in the United Kingdom — reports the new findings in the Journal of Autoimmunity.

Rheumatoid arthritis is an autoimmune disease that arises because the immune system attacks healthy tissue — usually the joints — by mistake, leading to painful inflammation and swelling.

The disease often affects several joints at the same time, such as the knees, hands, and wrists. It inflames the lining of the joint and eventually damages the joint itself. This can lead to long-lasting pain, problems with balance, and deformity.

Estimates suggest that approximately 1 percent of the world’s population has rheumatoid arthritis, including around 1.3 million adults in the United States. It affects women more often than men, raising the question of whether hormonal factors may be involved.
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No Weight-Loss Protection from Vitamin D – Tufts

I have said time and again that losing weight is not a good goal. Instead, work at living a  healthy life, eat intelligently and exercise regularly. Do that and you will never have to lose weight. I have been doing it since six months into writing this blog and now, eight years later, I have fluctuated about five pounds on either side of my 155 pound weight.

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This info from Tufts Health and Nutrition Letter, highlights postmenopausal women, but has wider implications.

While losing weight can protect you against chronic diseases, it does come with a downside – especially for postmenopausal women: Studies have shown that obese older women who lose weight also lose lean muscle mass and bone mineral density (BMD), particularly if they are inactive, potentially putting them at greater risk of frailty and falls. Continue reading

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Older men at risk of osteoporosis – Harvard

Because three out of four cases of osteoporosis are women, most people consider it a women’s disease,  especially men. However, as I reported here, after the age of 50 men are as likely to get osteoporosis as prostate cancer. More to the point, older people of both sexes have great vulnerability to it.

Here’s what Harvard Health Publications has to say:

Don’t think men need to worry about osteoporosis? Think again. In fact, about one in four men older than 50 will break a bone due to osteoporosis during their lifetime, according to the National Osteoporosis Foundation.

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How can men protect themselves and lower their risk of osteoporosis? Here are some strategies: Continue reading

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Two keys to strong bones … Harvard

Although bone-weakening osteoporosis is quite common among older people, it isn’t an inevitable part of aging. There’s a lot you can do to shield your bones from this disease.

While it is true that women account for most cases of osteoporosis. I think the fact that they outlive men, and the disease usually hits after late 50’s, because women outlive us, a disproportionate number of women get the disease. The International Osteoporosis Foundation says that worldwide, 1 in 3 women over age 50 will experience osteoporotic fractures, as will 1 in 5 men aged over 50.

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The best insurance against osteoporosis is building the highest bone density possible by your 30s and minimizing bone loss after that. But if you’re already in midlife or beyond, there is still much you can do to preserve the bone you have and perhaps even to replace lost bone. Daily weight-bearing exercise, like walking, is the best medicine. Getting enough calcium and vitamin D are two other critical strategies for keeping bones strong.

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Low Vitamin D may raise bladder cancer risk – Study

Vitamin D deficiency is associated with an increased risk of developing bladder cancer, according to a systematic review of seven studies led at the University of Warwick.

Five out of the seven studies linked low vitamin D levels to an increased risk of bladder cancer.

The researchers then looked at the cells that line the bladder, known as transitional epithelial cells, and found that these cells are able to activate and respond to vitamin D, which in turn can stimulate an immune response.

 

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Sources of Vitamin D

This is important because the immune system may have a role in cancer prevention by identifying abnormal cells before they develop into cancer. Lead author of the study Dr. Rosemary Bland said, “More clinical studies are required to test this association, but our work suggests that low levels of vitamin D in the blood may prevent the cells within the bladder from stimulating an adequate response to abnormal cells. Continue reading

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Vitamin D engages longevity gene to increase lifespan – Study

I  have written about the benefits of Vitamin D a number of times. You can check some of the links at the end of this post to read further. Now comes Neuroscience News with a report on  its possible impact on increased longevity.

Research in C. elegans shows the popular supplement engages longevity genes to increase lifespan and prevent the accumulation of toxic proteins linked to many age-related diseases.

A simple Google search for “what does vitamin D do?” highlights the widely used dietary supplement’s role in regulating calcium absorption and promoting bone growth. But now it appears that vitamin D has much wider effects — at least in the nematode worm, C. elegans. Research at the Buck Institute shows that vitamin D works through genes known to influence longevity and impacts processes associated with many human age-related diseases. The study, published in Cell Reports, may explain why vitamin D deficiency has been linked to breast, colon and prostate cancer, as well as obesity, heart disease and depression.

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“Vitamin D engaged with known longevity genes – it extended median lifespan by 33 percent and slowed the aging-related misfolding of hundreds of proteins in the worm,” said Gordon Lithgow, PhD, senior author and Buck Institute professor. “Our findings provide a real connection between aging and disease and give clinicians and other researchers an opportunity to look at vitamin D in a much larger context.” Continue reading

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Vitamin D – Do you get enough?

Vitamin D is considered by some to be the rock star of the vitamin world. To read further on its benefits check out: Vitamin D and Cognitive Function, Vitamin D Deficiency May be Linked to Heart Disease, Vitamin D Deficiency May Compromise Immune Function, Calcium and Vitamin D Help Hormones Help Bones, Vitamin D Improves Mood and Blood Pressure in Women with Diabetes, Vitamin D and Your Body – Harvard, What are the ABC’s of Vitamins?

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Tony

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Chemical Exposure Linked to Lower Vitamin D Levels – Study

Vitamin D has been called the rock star of vitamins. For an idea about all the good things our bodies get from vitamin D, check out these posts: How good is Vitamin D for you? Infographic, Vitamin D and your body – Harvard.

Exposure to bisphenol A (BPA) and other endocrine-disrupting chemicals (EDCs) may reduce levels of vitamin D in the bloodstream, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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The study is the first to find an association between EDC exposure and vitamin D levels in a large group of U.S. adults. EDCs are chemicals or mixtures of chemicals that can cause adverse health effects by interfering with hormones in the body. The Society’s Scientific Statement on EDCs examined more than 1,300 studies that found links between chemical exposure and health problems, including infertility, obesity, diabetes, neurological problems and hormone-related cancers. Continue reading

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Beyond Statins and CoQ10: How about Vitamins D and K2?

Some nice insights here on Statin drugs and vitamin depletion.

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