Category Archives: brain

Teeth brushing may fight Alzheimer’s

As a person with no less than three cases of Alzheimer’s/dementia in his family, I have serious interest in anything relating to maintaining brain health and function. So, I was most interested in this item from the University of Bergen.

You don’t only avoid holes in your teeth by keeping good oral hygiene, researchers at the University of Bergen have discovered a clear connection between gum disease and Alzheimer’s disease.

blur bristle brush clean

Photo by George Becker on Pexels.com

The researchers have determined that gum disease (gingivitis) plays a decisive role in whether a person develops Alzheimer’s or not.

“We discovered DNA-based proof that the bacteria causing gingivitis can move from the mouth to the brain,” says researcher Piotr Mydel at Broegelmanns Research Laboratory, Department of Clinical Science, University of Bergen (UiB).

The bacteria produces a protein that destroys nerve cells in the brain, which in turn leads to loss of memory and ultimately, Alzheimer’s. Continue reading

2 Comments

Filed under aging brain, brain, brain function, brain health, dental health

Reaching and grasping — Learning fine motor coordination changes the brain

When we train the reaching for and grasping of objects, we also train our brain. In other words, this action brings about changes in the connections of a certain neuronal population in the red nucleus, a region of the midbrain. Researchers at the University of Basel’s Biozentrum have discovered this group of nerve cells in the red nucleus. They have also shown how fine motor tasks promote plastic reorganization of this brain region. The results of the study have been published recently in Nature Communications.

brain.jpg

Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan’s research group at the Biozentrum, University of Basel, has investigated the red nucleus, a region of the midbrain that controls fine motor movement, and identified a new population of nerve cells which changes when fine motor coordination is trained. The more that grasping is practiced, the more the connections between the neurons of this group of nerve cells are strengthened. Continue reading

4 Comments

Filed under aging brain, brain, brain exercise, brain function

What about teen cannabis use – Study

gizmodo-high-tech-620x349.jpg

About one in five Canadian adolescents uses cannabis (19% of Canadians aged 15-19), and its recent legalization across the country warrants investigation into the consequence of this use on the developing brain. Adolescence is associated with the maturation of cognitive functions, such as working memory, decision-making, and impulsivity control. This is a highly vulnerable period for the development of the brain as it represents a critical period wherein regulatory connection between higher-order regions of the cortex and emotional processing circuits deeper inside the brain are established. It is a period of strong remodeling, making adolescents highly vulnerable to drug-related developmental disturbances. Research presented by Canadian neuroscientists Patricia Conrod, Steven Laviolette, Iris Balodis and Jibran Khokhar at the 2019 Canadian Neuroscience Meeting in Toronto on May 25 featured recent discoveries on the effects of cannabis on the adolescent brain.

Continue reading

Leave a comment

Filed under brain, brain function, brain health, cognition, marijuana, pot, weed

Researchers Define Alzheimer’s-like Brain Disorder

As regular readers know, I have a history of Alzheimer’s Disease or some form of dementia on both sides of my family, so I entertain a strong interest in the subject, particularly since I am a senior citizen.

neuroimaging-social-exclusion-radicalization-neuroscineews

A brain disorder that mimics symptoms of Alzheimer’s disease has been defined with recommended diagnostic criteria and guidelines for advancing future research on the condition. Researchers at Rush University Medical Center and scientists from several National Institutes of Health-funded institutions, in collaboration with international peers, described the newly named pathway to dementia, limbic-predominant age-related TDP-43 encephalopathy, or LATE, in a report published today in the journal Brain.

“We proposed a new name to increase recognition and research for this common cause of dementia, the symptoms of which mimic Alzheimer’s dementia but is not caused by plaques and tangles (the buildup of beta amyloid proteins that Alzheimer’s produces). Rather, LATE dementia is caused by deposits of a protein called TDP-43 in the brain,” said Dr. Julie Schneider, senior author of the Brain paper and associate director of the Rush Alzheimer’s Disease Center. Continue reading

1 Comment

Filed under aging brain, Alzheimer's disease, brain, brain function, dementia

Tufts on brain food

The science of whether some dietary choices can be considered brain food or not continues to unfold.

Given long time-frames of conditions such as Alzheimer’s disease and other dementias, it’s challenging to prove any cause and effect relationship between specific foods and brain health. Most such associations are drawn from observational studies, in which people who eat more or less of a certain food are assessed over time for cognitive changes.

berries blackberries blueberries bowls

Photo by Pixabay on Pexels.com

It’s obviously difficult to feed a group of study participants lots of, say, blueberries for several years in order to test their brain health at the end; that’s why clinical trials of so-called brain foods have largely depended on animal tests.

Nonetheless, some foods tend to stand out from the pages and pages of research results as most likely being protective for brain health. Continue reading

1 Comment

Filed under brain, brain function, brain health, nuts

Is it possible to supercharge memories back to life? – BU Study

As a 79 year old bike rider, I know how much I am counting on exercise to keep my brain intact as I age. So, I was nothing less than amazed to run across the Boston University (BU) study on electrically stimulating brain function in seniors.

BU brain scientist shows electrostimulation can restore a 70-year-old’s working memory to that of a 20-year-old.

photo of head bust print artwork

Photo by meo on Pexels.com

As you read the words stretched across this page, your brain is doing something magnificent. Each sentence lingers in your mind for a fleeting moment, the letters melding into a symphony of neural signals. These intricate electrical rhythms form the language of the brain, a language we have only begun to understand within the last century.

Rob Reinhart, an assistant professor of psychological and brain sciences at Boston University, says we’ve reached a point where we not only understand this language—we can speak it and harness it to enhance the functioning of the mind. In a groundbreaking study published April 2019 in Nature Neuroscience, Reinhart and BU doctoral researcher John Nguyen demonstrate that electrostimulation can improve the working memory of people in their 70s so that their performance on memory tasks is indistinguishable from that of 20-year-olds.

Reinhart and Nguyen’s research targets working memory—the part of the mind where consciousness lives, the part that is active whenever we make decisions, reason, recall our grocery lists, and (hopefully) remember where we left our keys. Working memory starts to decline in our late 20s and early 30s, Reinhart explains, as certain areas of the brain gradually become disconnected and uncoordinated. By the time we reach our 60s and 70s, these neural circuits have deteriorated enough that many of us experience noticeable cognitive difficulties, even in the absence of dementias like Alzheimer’s disease. Continue reading

4 Comments

Filed under aging brain, Boston University, brain, brain function, brain health, electrostimulation

Brain health connects to heart health – CDC

Eat less; move more; live longer is the mantra here. Apparently, it also leads to think better, too. The Centers for Disease Control and Prevention (CDC) seems to think so.

Did you know that the health of your brain and your heart are connected? By keeping your heart healthy, you also lower your risk for brain problems such as stroke and dementia. Learn more about the connection between the heart and brain and steps to take to keep both healthy.

woman in white cap shirt on stability ball

Photo by Public Domain Pictures on Pexels.com

Heart disease, stroke, and vascular dementia are preventable. Take steps to reduce your risk.

 

  • Control your blood pressure. High blood pressure is a leading cause of heart disease and stroke. Over time, high blood pressure puts too much stress on blood vessels. Scientists now know that having uncontrolled high blood pressure in midlife also raises your risk for dementia later in life. Know your numbers by getting your blood pressure checked regularly. If your blood pressure is high, work with your doctor, nurse, or health care team to manage it. One way to manage your blood pressure is to take your medicines as prescribed. Learn more ways to manage blood pressure.
  • Eat healthy foods and limit alcohol. Eat plenty of vegetables, fruits, whole grains, and low-fat dairy, and include seafood rich in omega-3 fatty acids (such as salmon) each week. Limit foods with added sugars and saturated fats, and lower your sodium (salt) intake. If you drink alcohol, drink in moderation. Drinking too much alcohol raises blood pressure, which can lead to stroke and increase the risk of some kinds of heart disease.
  • Get diabetes under control. Diabetes causes high blood sugar, which can damage blood vessels and nerves. This damage raises the risk for heart disease, stroke, and dementia.
  • Don’t smoke. Smoking damages blood vessels and makes blood more likely to clot, which can lead to heart disease and stroke. Smoking is the leading cause of preventable death in the United States. If you don’t smoke, don’t start. If you do smoke, learn how to quit.
  • Stay active. Lack of physical activity can lead to high blood pressure and obesity. Most Americans don’t meet guidelines of getting at least 150 minutes of moderate-intensity exercise each week. Find ways to get your heart pumping for at least 150 minutes per week. Take the stairs, schedule a walk at lunch, or do jumping jacks during commercial breaks. Learn more about how to get enough physical activity.

2 Comments

Filed under aging brain, brain, brain function, brain health, dementia, Exercise, exercise benefits

Neuroplasticity – one brainy word

Since I had that nice infographic on the brain yesterday, I thought this one on brain function might be a useful follow-up.

NICABM-Neuroplasticity-Infographic-1.jpg

If you are interested in reading more about that wonderful organ inside your head, feel free to check out my Page – Important facts about your brain (and exercise benefits)

Tony

Leave a comment

Filed under brain, brain damage, brain function, brain health, neuroplasticity

Thinking about your brain – infographic

I love this infographic of the brain. Surprisingly, they left out one of the most impressive facts to me, namely, that the brain burns 20 to 25 percent of our daily calories. Bigger than any single muscle.

neilleslieinfo2_12001.jpg

Before you go, please check out my Page – Important facts about your brain (and exercise benefits) for a lot more details on this major organ in our body.

Tony

Leave a comment

Filed under brain, brain health, exercise and brain health, Healthy brain

Physics explains why time flies as we age

Time flies when you’re having fun. As an old timer, I have responded countless times that “Time flies even when you’re not having fun.” So I was most gratified to find this research on exactly that.

A Duke University researcher has a new explanation for why those endless days of childhood seemed to last so much longer than they do now–physics.

According to Adrian Bejan, the J.A. Jones Professor of Mechanical Engineering at Duke, this apparent temporal discrepancy can be blamed on the ever-slowing speed at which images are obtained and processed by the human brain as the body ages.

Screen Shot 2019-03-21 at 5.06.54 PM.png

The end result is that, because older people are viewing fewer new images in the same amount of actual time, it seems to them as though time is passing more quickly. 

The theory was published online on March 18 in the journal European Review. Continue reading

4 Comments

Filed under aging, aging brain, brain, brain function, successful aging, time flies

Better brain aging through diet – Tufts

I have spent a lot of time writing about the benefits of exercise for the brain as well as the body. Herewith info from the Tufts Health and Nutrition Letter on what I can only call food for thought.

Currently available medical treatments for age-related cognitive decline and Alzheimer’s disease have had limited success. Adopting a healthy diet and lifestyle has been among the most consistent recommendations to maintain brain health over the long term. Some studies have linked an overall healthy dietary pattern to less chance of experiencing age-related decline in memory and other cognitive skills.

brain

The specifics of “brain protective” diets vary, but tend to have certain elements in common. Dietary patterns associated with lower risk of age-related cognitive decline and dementia are higher in non-starchy vegetables, fruits, whole grains, nuts, legumes and seafood while limited in red and/or processed meats, sugar-sweetened foods and drinks, refined grains and added salt.

But there have been few long-term trials testing overall dietary patterns for protecting the aging brain. Researchers at Rush University Medical Center in Chicago and the Harvard T.H. Chan School of Public Health are currently conducting a clinical trial of a diet specifically optimized for brain health and mild weight loss—the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet.

If successful, the result of the MIND trial will provide older adults with more specific nutritional guidance to maintain their cognitive health. “What they’re doing is logical and I predict will have positive benefits for a disease for which we have few interventions,” notes Dennis Steindler, PhD, senior scientist and director of Tufts’ HNRCA Neuroscience and Aging Laboratory. “Past trials were not home runs, but this study could be it if it bears the kind of findings I think it will.” Continue reading

4 Comments

Filed under aging brain, brain, brain health, food choices, MIND diet, Tufts University

Keeping active in middle age may be tied to lower risk of dementia – Study

In the nearly 10 years of writing this blog I have come to believe that use it or lose it is an unassailable law of the body. And what applies to the body often carries over to the brain. As I have mentioned previously, my family has dementia in general and Alzheimer’s in particular on both sides, so keeping a clear head really resonates with me.

Screen Shot 2019-02-26 at 8.36.25 PM.png

My dog and me out for a ride. I am a little past middle age in the picture, but you get the idea.

Keeping physically and mentally active in middle age may be tied to a lower risk of developing dementia decades later, according to a study published in the medical journal Neurology. Mental activities included reading, playing instruments, singing in a choir, visiting concerts, gardening, doing needlework or attending religious services.

“These results indicate that these activities in middle age may play a role in preventing dementia in old age and preserving cognitive health,” said study author Jenna Najar, MD, from Sahlgrenska Academy, University of Gothenburg.

“It’s exciting as these are activities that people can incorporate into their lives pretty easily and without a lot of expense.” Continue reading

3 Comments

Filed under aging brain, brain, brain function, dementia, exercise and brain health, exercise benefits

Optical illusion tricks brain – Study

I really wanted to reproduce this just because the illusion seemed so cool to me. I don’t know that you can benefit from in any way, but to enjoy it. Follow the directions in the caption – and enjoy.

Summary: Researchers report the same subset of neurons encode actual and illusory flow motion, supporting the concept Jan Purkinje proposed 150 years ago, that “illusions contain visual truth”.Source: SfN.

A study of humans and monkeys published in Journal of Neuroscience has found the same subset of neurons encode actual and illusory complex flow motion. This finding supports, at the level of single neurons, what the Czech scientist Jan Purkinje surmised 150 years ago: “Illusions contain visual truth.”

 

Screen Shot 2019-02-18 at 1.53.10 PM.png

Fixate the black dot and move your head towards and away from the image and you should perceive the rings rotating. NeuroscienceNews.com image is credited to Junxiang Luo.

The Pinna-Brelstaff figure is a static image of rings that appear to rotate clockwise as one moves toward and counterclockwise as one moves away from the figure. Having previously identified particular parts of the human brain that represent the Pinna illusion, Junxiang Luo and colleagues at the Institute of Neuroscience, Chinese Academy of Sciences first confirmed that male rhesus macaques likely perceive the illusion similarly to people.

The researchers then recorded activity from individual neurons in the previously identified brain regions, and discovered cells that signal the illusory motion similarly to actual motion. A delay of about 15 milliseconds enables the brain to register the illusory motion as if it was real.

This study provides new insights into how the brain grapples with the continual mismatch between perception and reality.

Leave a comment

Filed under brain, brain exercise, Healthy brain, optical illusion

Alzheimer’s blood test detects brain damage years before symptoms – Study

A blood test for a protein could identify people in the early stages of Alzheimer’s disease a decade or more before symptoms, such as a decline in memory and thinking, emerge, as reported in Medical News Today.

This was what an international group of scientists concluded after evaluating the simple test that used blood samples from people with a rare form of Alzheimer’s disease that they had inherited.

The team included researchers from Washington University School of Medicine in St. Louis, MO and the German Center for Neurodegenerative Diseases in Tübingen, Germany.

The test looks for changes in levels of the neurofilament light chain (NfL) protein. The protein normally resides inside brain cells, or neurons, as part of their internal skeleton.

person holding string lights photo

Photo by David Cassolato on Pexels.com

However, damaged and dying cells can leak NfL into surrounding cerebrospinal fluid. The protein then travels from the fluid into the bloodstream. Continue reading

2 Comments

Filed under aging brain, Alzheimer's, Alzheimer's disease, blood test, brain, cognition, cognitive decline

Emergency and Urgent Hospitalizations Linked to Accelerated Cognitive Decline in Seniors

My interest in cognition and cognitive decline, particularly in seniors brought me to this amazing study. I think it may give further import to the idea of maintaining a physically  active life into our senior years,

Emergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at Rush University Medical Center. Results of their study, published in the Jan. 11, 2019, online issue of Neurology shows that hospitalization may be a more of a major risk factor for long-term cognitive decline in older adults than previously recognized.

bed empty equipments floor

Photo by Pixabay on Pexels.com

“We found that those who have non-elective (emergency or urgent) hospitalizations and who have not previously been diagnosed with dementia or Alzheimer’s disease had a rapid decline in cognitive function (i.e., thinking abilities) compared to the pre-hospital rates,” said Bryan James, PhD, an epidemiologist and in the Rush Alzheimer’s Disease Center and an assistant professor in the Rush Department of Internal Medicine. “By comparison, people who were never hospitalized and those who had elective hospitalizations did not experience the drastic decline in cognitive function.” Continue reading

2 Comments

Filed under aging brain, brain, brain function, cognition, cognitive decline

Social Exclusion Spurs Extremism in Those Vulnerable to Radicalization – Study

Summary: A neuroimaging study reveals the effects of social exclusion in the left inferior frontal gyrus. The study found social exclusion can spur extremist behaviors in people who are most vulnerable to radicalization. Source: Universitat Autònoma de Barcelona.

A study led by researchers from the Universitat Autònoma de Barcelona (UAB) and the Hospital del Mar Medical Research Institute (IMIM), in collaboration with other international institutions, explored the neural and behavioral relationships between sacred values, violent extremism and social exclusion in a group of young Moroccan men living and schooled in Catalonia and vulnerable to radicalization.

neuroimaging-social-exclusion-radicalization-neuroscineews.jpg

A study conducted by the UAB and IMIM used neuroimaging techniques to show that social exclusion increases the number of ideological and group values worth fighting and dying for in populations vulnerable to radicalisation. The study focused on neural activity in a region of the brain related to rule retrieval and sacred values. NeuroscienceNews.com image is in the public domain.Sacred values are those perceived as non-negotiable, those which must be upheld at all costs. They also contain an identity component related to perceiving the person as a member of their reference group.

Continue reading

Leave a comment

Filed under brain, brain health, President Trump, social exclusion, Trump