Category Archives: brain

Alzheimer’s blood test detects brain damage years before symptoms – Study

A blood test for a protein could identify people in the early stages of Alzheimer’s disease a decade or more before symptoms, such as a decline in memory and thinking, emerge, as reported in Medical News Today.

This was what an international group of scientists concluded after evaluating the simple test that used blood samples from people with a rare form of Alzheimer’s disease that they had inherited.

The team included researchers from Washington University School of Medicine in St. Louis, MO and the German Center for Neurodegenerative Diseases in Tübingen, Germany.

The test looks for changes in levels of the neurofilament light chain (NfL) protein. The protein normally resides inside brain cells, or neurons, as part of their internal skeleton.

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However, damaged and dying cells can leak NfL into surrounding cerebrospinal fluid. The protein then travels from the fluid into the bloodstream. Continue reading

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Emergency and Urgent Hospitalizations Linked to Accelerated Cognitive Decline in Seniors

My interest in cognition and cognitive decline, particularly in seniors brought me to this amazing study. I think it may give further import to the idea of maintaining a physically  active life into our senior years,

Emergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at Rush University Medical Center. Results of their study, published in the Jan. 11, 2019, online issue of Neurology shows that hospitalization may be a more of a major risk factor for long-term cognitive decline in older adults than previously recognized.

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“We found that those who have non-elective (emergency or urgent) hospitalizations and who have not previously been diagnosed with dementia or Alzheimer’s disease had a rapid decline in cognitive function (i.e., thinking abilities) compared to the pre-hospital rates,” said Bryan James, PhD, an epidemiologist and in the Rush Alzheimer’s Disease Center and an assistant professor in the Rush Department of Internal Medicine. “By comparison, people who were never hospitalized and those who had elective hospitalizations did not experience the drastic decline in cognitive function.” Continue reading

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Social Exclusion Spurs Extremism in Those Vulnerable to Radicalization – Study

Summary: A neuroimaging study reveals the effects of social exclusion in the left inferior frontal gyrus. The study found social exclusion can spur extremist behaviors in people who are most vulnerable to radicalization. Source: Universitat Autònoma de Barcelona.

A study led by researchers from the Universitat Autònoma de Barcelona (UAB) and the Hospital del Mar Medical Research Institute (IMIM), in collaboration with other international institutions, explored the neural and behavioral relationships between sacred values, violent extremism and social exclusion in a group of young Moroccan men living and schooled in Catalonia and vulnerable to radicalization.

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A study conducted by the UAB and IMIM used neuroimaging techniques to show that social exclusion increases the number of ideological and group values worth fighting and dying for in populations vulnerable to radicalisation. The study focused on neural activity in a region of the brain related to rule retrieval and sacred values. NeuroscienceNews.com image is in the public domain.Sacred values are those perceived as non-negotiable, those which must be upheld at all costs. They also contain an identity component related to perceiving the person as a member of their reference group.

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Number of People with Dementia Has Doubled in Sixteen Years

The number of people living with dementia globally more than doubled between 1990 and 2016 from 20.2 million to 43.8 million, prompting researchers to call for more preventative action.

A new paper published in The Lancet Neurology also found that 22.3 per cent of healthy years lost due to dementia in 2016 were due to modifiable risk factors.

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Prepared by academics across multiple institutions and led by the University of Melbourne and the University of Washington, the paper looked at the global, regional and national burden of Alzheimer’s Disease and other dementias from 1990-2016.

The systematic analysis of the Global Burden of Disease Study 2016 found dementia was more common at older ages, with the prevalence doubling every five years over age 50. There was also significant potential for prevention.

“In our study, 22.3 per cent (11.8 – 35.1 per cent) of the total global disability-adjusted life years lost due to dementia in 2016 could be attributed to the four modifiable risk factors – being overweight, high blood sugar, consuming a lot of sugar sweetened beverages and smoking,” the authors said.

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Regular exercise changes the brain – Harvard

Eat less; move more; live longer remains the mantra of this blog. It is good to learn from Harvard, no less, that moving more also helps to keep our brain intact and functioning.

There are plenty of good reasons to be physically active. Big ones include reducing the odds of developing heart disease, stroke, and diabetes. Maybe you want to lose weight, lower your blood pressure, prevent depression, or just look better. Here’s another one, which especially applies to those of us (including me) experiencing the brain fog that comes with age: exercise changes the brain in ways that protect memory and thinking skills.

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In a study done at the University of British Columbia, researchers found that regular aerobic exercise, the kind that gets your heart and your sweat glands pumping, appears to boost the size of the hippocampus, the brain area involved in verbal memory and learning. Resistance training, balance and muscle toning exercises did not have the same results.

The finding comes at a critical time. Researchers say one new case of dementia is detected every four seconds globally. They estimate that by the year 2050, more than 115 million people will have dementia worldwide. Continue reading

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Just 6 months of moderate exercise may boost an aging brain – Study

Getting the heart pumping with aerobic exercise, like walking or cycling for 35 minutes three times a week, may improve thinking skills in older adults with cognitive impairments, according to a study published in the December 19, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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After six months of exercise, study participants’ scores on thinking tests improved by the equivalent of reversing nearly nine years of aging. The study looked at people who had cognitive impairments without dementia, which is defined as having difficulty concentrating, making decisions, or remembering, but not severe enough to be diagnosed with dementia.

The study found that exercise improved thinking skills called executive function. Executive function is a person’s ability to regulate their own behavior, pay attention, organize and achieve goals. Continue reading

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Merry Christmas and Season’s Greetings!

I hope this edible Christmas tree will give you healthy ideas about your eating this holiday season and in the coming year.

While you are thinking about it, don’t forget that you need to exercise, too. You won’t be exercising just to burn calories. Exercise benefits your brain and body in many ways. Check out the exercise tags at the right to read further on this.

I hope you will enjoy all the benefits of good food and exercise! Eat less; move more; live longer. Healthy eating is healthy aging and we all want that. Okay, we seniors are more aware of it than you younger folk, but keep at it and you will come realize and appreciate it too.

Best wishes for this holiday season!

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Tony

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Drawing is Better than Writing for Memory Retention – Study

Regular readers know that I am a senior citizen, turning 79 next month. My family has a history of dementia in general and Alzheimer’s Disease in particular. SO, I am interested in anything that affects the brain and relates to brain function. This study at the University of Waterloo captured my attention.

Researchers report older adults who take up drawing are better able to retain new information than those who write notes.Source: University of Waterloo.

Older adults who take up drawing could enhance their memory, according to a new study.

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As part of a series of studies, the researchers asked both young people and older adults to do a variety of memory-encoding techniques and then tested their recall. NeuroscienceNews.com image is in the public domain.

Researchers from the University of Waterloo found that even if people weren’t good at it, drawing, as a method to help retain new information, was better than re-writing notes, visualization exercises or passively looking at images. Continue reading

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Yoga breathing exercises can sharpen your mind – Study

Breath-focused meditation and yogic breathing practices have numerous known cognitive benefits, including increased ability to focus, decreased mind wandering, improved arousal levels, more positive emotions, decreased emotional reactivity, along with many others. To date, however, no direct neurophysiological link between respiration and cognition has been suggested.

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The research shows for the first time that breathing – a key element of meditation and mindfulness practices – directly affects the levels of a natural chemical messenger in the brain called noradrenaline. This chemical messenger is released when we are challenged, curious, exercised, focused or emotionally aroused, and, if produced at the right levels, helps the brain grow new connections, like a brain fertilizer. The way we breathe, in other words, directly affects the chemistry of our brains in a way that can enhance our attention and improve our brain health.

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Eyes provide new lens for Alzheimer’s screening

At the risk of repeating myself I have a strong interest in any form of dementia and especially Alzheimer’s Disease as I have had at least three close family members succumb – and I am a senior citizen.  the folowing is from the University of Washington School of Medicine.

Alzheimer’s disease is difficult to diagnose as well as treat,  but researchers now have a promising new screening tool using the window to the brain:  the eye.

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A study of 3,877 randomly selected patients found a significant link between three degenerative eye diseases – age-related macular degeneration, diabetic retinopathy and glaucoma – and Alzheimer’s disease.

The results offer physicians a new way to detect  those at higher risk of this disorder, which causes memory loss and other symptoms of cognitive decline. Continue reading

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Alzheimer’s Genetically Linked to Cardiovascular Disease – Study

Studying DNA from more than 1.5 million people, an international team of researchers — led by Washington University School of Medicine in St. Louis and the University of California, San Francisco — has identified points of DNA that increase the risk of cardiovascular disease and also heighten the risk for Alzheimer’s disease, according to an article in Neuroscience News.

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Scientists have long been aware of connections between variations of the APOE gene, which is involved in cholesterol and lipid metabolism, and Alzheimer’s disease. That gene is known to double the risk for Alzheimer’s disease in some patients and increase risk by up to 12 times in others. But in the new study, the researchers identified other DNA points that also appear to be involved both in cardiovascular disease risk and the risk for Alzheimer’s. Continue reading

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Exercise and be happy – Infographic

I have written so many times about the benefits of exercise on the body and brain that this almost seems repetitious. On the other hand, it is nice to see the exact hormones at work.

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On the off chance that you are not familiar with it, please check out my Page – Important facts about your brain – (and exercise benefits.)

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Tony

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How coffee protects the brain

I am guilty of being a coffee lover. I am so bad that when I see someone on TV carrying a cardboard cup of the brew, I am tempted to make some for myself. So, the following was good news for me.

Scientists have now proved that drinking certain types of coffee can be beneficial to brain health, but how does this popular brew support cognitive function? A new study identifies some of the mechanisms that allow coffee to keep mental decline at bay.

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According to data from the Harvard T.H. Chan School of Public Health in Boston, MA, about 54 percent of all adults in the United States drink coffee on a daily basis.

While drinking coffee can bring both benefits and risks for a person’s health, a 2016 study from the University of Ulster in Coleraine, United Kingdom, concluded that the health benefits of moderate coffee consumption “clearly outweigh” the potential risks.

One of these benefits is that coffee seems to protect the brain against cognitive impairments and boost thinking skills. Continue reading

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Cognitive stress test can show high level of beta-amyloid

We are eating less; moving more and hopefully living longer, but it is imperative that we have a fully functioning brain or our work will be in vain.

A simple and inexpensive word recall test accurately predicted whether people had elevated brain levels of beta-amyloid. Scientists hope this non-invasive stress test that puts pressure on memory–similar to how an exercise stress test checks cardiovascular health–could help identify subtle signs of cognitive impairment that may have previously been missed by standard memory tests.

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An NIA-supported team of researchers led by Dr. David Loewenstein of the Center for Cognitive Neurosciences and Aging and the University of Miami Miller School of Medicine developed the Loewenstein-Acevedo Scales for Semantic Interference and Learning (LASSI-L) test. Their preliminary findings were published in the September 4, 2018 issue of Neurology.

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AI Could Soon Predict Cognitive Decline Leading to Alzheimer’s Disease – Study

A team of scientists has successfully trained a new artificial intelligence (AI) algorithm to make accurate predictions regarding cognitive decline leading to Alzheimer’s disease.

Dr. Mallar Chakravarty, a computational neuroscientist at the Douglas Mental Health University Institute, and his colleagues from the University of Toronto and the Center for Addiction and Mental Health, designed an algorithm that learns signatures from magnetic resonance imaging (MRI), genetics, and clinical data. This specific algorithm can help predict whether an individual’s cognitive faculties are likely to deteriorate towards Alzheimer’s in the next five years.

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“At the moment, there are limited ways to treat Alzheimer’s and the best evidence we have is for prevention. Our AI methodology could have significant implications as a ‘doctor’s assistant’ that would help stream people onto the right pathway for treatment. For example, one could even initiate lifestyle changes that may delay the beginning stages of Alzheimer’s or even prevent it altogether,” says Chakravarty, an Assistant Professor in McGill University’s Department of Psychiatry. Continue reading

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10 Top brain power foods

I don’t know if these really will increase your brain power, but I don’t see any harm in letting you know about them.

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Please let me know if you have any experience with these.To my knowledge they are all excellent foods nutritionally.

Tony

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