Tag Archives: longevity

Physical Frailty Syndrome – Aging –

“There is strong evidence that frailty is both prevented and ameliorated by physical activity, with or without a Mediterranean diet or increased protein intake,” noted Fried. “These model interventions to date are nonpharmacologic, behavioral ones, emphasizing the potential for prevention through a complex systems approach.” 

In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related pathophysiology underpinning the clinical presentation of phenotypic frailty (termed as “physical frailty” here) is a state of lower functioning due to severe dysregulation of the complex dynamics in our bodies that maintains health and resilience. When severity passes a threshold, the clinical syndrome and its phenotype are diagnosable. This paper summarizes the evidence meeting criteria for physical frailty as a product of complex system dysregulation. This clinical syndrome is distinct from the cumulative-deficit-based frailty index of multimorbiditys. The paper is published online here.

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Physical frailty is defined as a state of depleted reserves resulting in increased vulnerability to stressors that emerges during aging independently of any specific disease. It is clinically recognizable through the presence of three or more of five key clinical signs and symptoms: weakness, slow walking speed, low physical activity, exhaustion and unintentional weight loss.

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Smart food choices

Following these tips can help you maintain a healthy weight, get the nutrients you need, and lower your risk of chronic disease.

  • Try to eat and drink from these food groups each day: fruits, vegetables, grains, protein, and dairy. Variety is an important part of eating healthfully!
  • Cut back on foods and beverages that are high in calories and added sugars, sodium, and saturated fats. Shift to healthier options like fresh fruits and vegetables instead.
  • Instead of high-calorie snacks, such as potato chips, try nutrient-dense snacks, such as carrots.
  • Instead of fruit products with added sugars, such as fig cookies, try fresh fruit, such as a peach.
  • Instead of regular cola, try water flavored with fruits or vegetables.
  • Use a food diary to help you keep track of your total daily calories, carbs, protein, etc., and see if you are making healthy choices. Understand how many calories you need based on your level of daily activity.
  • Choose a variety of foods that are packed with nutrients and low in calories.
  • Check the food labels to understand what foods will meet your nutritional needs each day.

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Study identifies countries and states with greatest age biases

As a guy in his early 80’s working every day on making it into his ’90’s, I found it kind of disturbing that here in the States elders aren’t necessarily held in very high regard.

Elders are more respected in Japan and China and not so much in more individualistic nations like the United States and Germany, say Michigan State University researchers who conclude in a pair of studies that age bias varies among countries and even states.

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“Older adults are one of the only stigmatized groups that we all become part of some day. And that’s always struck me as interesting — that we would treat so poorly a group of people that we’re destined to become someday,” said William Chopik, assistant professor of psychology and author of the studies. “Making more equitable environments for older adults are even in younger people’s self-interests.”

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People who eat chili pepper may live longer?

  • Consumption of chili pepper may reduce the relative risk of cardiovascular disease mortality by 26%, according to an analysis of diet and mortality data from four large, international studies.
  • Chili pepper consumption was associated with a 25% reduction in death from any cause and 23% fewer cancer deaths, compared to people who never or only rarely consumed chili pepper.
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Individuals who consume chili pepper may live longer and may have a significantly reduced risk of dying from cardiovascular disease or cancer, according to preliminary research to be presented at the American Heart Association’s Scientific Sessions 2020. The meeting will be held virtually, Friday, November 13-Tuesday, November 17, 2020, and is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science for health care worldwide.

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Blood Vitamin D levels can predict future health risks and death

Free, circulating Vitamin D levels in the blood may be a better predictor of future health risks in aging men, according to a study being presented at e-ECE 2020. These data suggest the free, precursor form of vitamin D found circulating in the bloodstream is a more accurate predictor of future health and disease risk, than the often measured total Vitamin D. Since Vitamin D deficiency is associated with multiple serious health conditions as we get older, this study suggests that further investigation into Vitamin D levels and their link to poor health may be a promising area for further research.

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Vitamin D deficiency is common in Europe, especially in elderly people. It has been associated with a higher risk for developing many aging-related diseases, such as cardiovascular disease, cancer and osteoporosis. However, there are several forms, or metabolites, of Vitamin D in the body but it is the total amount of these metabolites that is most often used to assess the Vitamin D status of people. The prohormone, 25-dihydroxyvitamin D is converted to 1,25-dihydroxyvitamin D, which is considered the active form of vitamin D in our body. More than 99% of all Vitamin D metabolites in our blood are bound to proteins, so only a very small fraction is free to be biologically active. Therefore the free, active forms may be a better predictor of current and future health.

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Diets high in protein linked to lower risk of death

Diets high in protein, particularly plant protein, are associated with a lower risk of death from any cause, finds an analysis of the latest evidence published by The BMJ.

The researchers say these findings “support current dietary recommendations to increase consumption of plant proteins in the general population.”

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Diets high in protein, particularly protein from plants such as legumes (peas, beans and lentils), whole grains and nuts, have been linked to lower risks of developing diabetes, heart disease and stroke, while regular consumption of red meat and high intake of animal proteins have been linked to several health problems.

But data on the association between different types of proteins and death are conflicting.

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Living environment may be key to longevity – Study

When it comes to living to the ripe old age of 100, good genes help but don’t tell the full story. Where you live has a significant impact on the likelihood that you will reach centenarian age, suggests a new study conducted by scientists at Washington State University’s Elson S. Floyd College of Medicine.

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Published in the International Journal of Environmental Research and Public Health and based on Washington State mortality data, the research team’s findings suggest that Washingtonians who live in highly walkable, mixed-age communities may be more likely to live to their 100th birthday. They also found socioeconomic status to be correlated, and an additional analysis showed that geographic clusters where the probability of reaching centenarian age is high are located in urban areas and smaller towns with higher socioeconomic status, including the Seattle area and the region around Pullman, Wash.

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Exercise may slow seniors’ brain aging 10 years

Exercise in older people is associated with a slower rate of decline in thinking skills that occurs with aging. People who reported light to no exercise experienced a decline equal to 10 more years of aging as compared to people who reported moderate to intense exercise, according to a population-based observational study published in the online issue of Neurology®, the medical journal of the American Academy of Neurology.

“The number of people over the age of 65 in the United States is on the rise, meaning the public health burden of thinking and memory problems will likely grow,” said study author Clinton B. Wright, MD, MS, of the University of Miami in Miami, Fla., and member of the American Academy of Neurology. “Our study showed that for older people, getting regular exercise may be protective, helping them keep their cognitive abilities longer.”

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New Tool Measures Pace of Aging Across Life Course

A study just released by Columbia University Mailman School of Public Health researchers is reporting a blood-DNA-methylation measure that is sensitive to variation in the pace of biological aging among individuals born the same year. The tool—DunedinPoAm—offers a unique measurement for intervention trials and natural experiment studies investigating how the rate of aging may be changed by behavioral or drug therapy, or by changes to the environment. Study findings are published online in the journal e-Life.

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“The goal of our study was to distill a measurement of the rate of biological aging based on 12 years of follow-up on 18 different clinical tests into a blood test that can be administered at a single time point,” says lead author Daniel Belsky, PhD, assistant professor of epidemiology at Columbia Mailman School and a researcher at the Butler Columbia Aging Center.

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Number of steps per day more important than step intensity

I have written repeatedly about the benefits of walking, calling it the ‘Cinderella of the exercise world.’ Now, according the the National Institutes of Health (NIH), it seems that quantity equals quality in walking.

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  • Adults who took 8,000 or more steps a day had a reduced risk of death over the following decade than those who only walked 4,000 steps a day.
  • Step intensity (number of steps per minute) didn’t influence the risk of death, suggesting that the total number of steps per day is more important than intensity.

Doctors often recommend walking as an easy way for inactive people to ease into better health. Taking 4,000 or fewer steps a day is considered a low level of physical activity. A goal of 10,000 steps a day is commonly cited, but recent studies have shown that health benefits accrue even if fewer than 10,000 steps are taken daily. Continue reading

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How Well You Age Is All About Attitude, Says New Global Study

Our Better Health

VANCOUVER—A simple shift in attitude could improve a lot for the world’s elderly population, according to a new global study.

That’s because how well we age is connected to how we view old age, the study stated, noting those with a positive attitude toward old age are likely to live longer — up to eight years — than their negative counterparts.

And older people in countries with low levels of respect for seniors are at risk for worse mental and physical health as well as higher levels of poverty, the Orb Media study found. By compiling global data, researchers also surveyed 150,000 people in 101 countries to discover levels of respect for older adults, which varied from country to country.

Canada ranked in the lower third of all for respect, along with Japan, the United Kingdom and the United States.

But one British Columbian expert pointed out that the…

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Deaths in middle-aged adults drive decrease in U.S. life expectancy – Study

Americans in the prime of life, age 25 to 64, are dying at a greater rate than in years past, lowering overall U.S. life expectancy, according to a new study published Nov. 26 in JAMA.

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Life expectancy — the average number of years a newborn can expect to live — increased in the U.S. by almost 10 years between 1959 and 2016, from 69.9 years to 78.9 years. However, it declined for three consecutive years after 2014, driven largely by a higher mortality rate in middle-aged people of all racial groups.

In the NIA-supported study, researchers at Virginia Commonwealth University analyzed data from the National Center for Health Statistics, the U.S. Mortality Database, and CDC Wonder. They found that from 1999 to 2010, the number of deaths per 100,000 people decreased for all age groups. This decline is attributable to reduced death rates from several specific causes, including heart attacks, motor vehicle injuries, HIV infection and cancer.

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Do dog owners live longer? – AHA

As a dog owner, I absolutely have a bias on this subject. Also, I want to credit Learning from Dogs, Paul Handover’s fine blog for first publishing this as a part of one of his posts.

Dog owners have better results after a major health event.

The studies found that, overall, dog owners tend to live longer than non-owners. And they often recover better from major health events such as heart attack or stroke, especially if they live alone.

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This is my dog, Gabi, sitting in her basket on one of our rides.

As dog lovers have long suspected, owning a canine companion can be good for you. In fact, two recent studies and analyses published in Circulation: Cardiovascular Quality and Outcomes, a scientific journal of the American Heart Association, suggest your four-legged friend may help you do better after a heart attack or stroke and may help you live a longer, healthier life. And that’s great news for dog parents!

Some exciting stats for dog owners: Continue reading

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Every minute of exercise affects longevity – Study

Clear evidence that higher levels of physical activity – regardless of intensity – are associated with a lower risk of early death in middle aged and older people, is published by The BMJ Today. But being sedentary for several hours a day linked to increased risk.

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The findings also show that being sedentary, for example sitting still, for 9.5 hours or more a day (excluding sleeping time) is associated with an increased risk of death.

Previous studies have repeatedly suggested that sedentary behavior is bad and physical activity is good for health and long life.

Guidelines recommend at least 150 minutes of moderate intensity or 75 minutes of vigorous physical activity each week, but are based mainly on self reported activity, which is often imprecise. So exactly how much activity (and at what intensity) is needed to protect health remains unclear. Continue reading

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Gain years keeping heart disease at bay – AHA

Heart disease is the nation’s No. 1 cause of death, killing about 650,000 people every year. Life expectancy is cut short by the disease and the health problems that stem from it. But by how much – and what can people do to take those years back?

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For heart attacks alone, more than 16 years of life are lost on average, according to American Heart Association statistics. Researchers estimate people with heart failure lose nearly 10 years of life compared to those without heart failure.

“In the past few years, there have been tremendous gains in reducing cardiovascular disease and increasing life expectancy, but we’ve hit a plateau,” said Paul Muntner, an epidemiologist at the University of Alabama at Birmingham.

Some people are at greater risk than others.

African Americans, for example, are more likely to have high blood pressure, obesity and diabetes, and they live 3.4 years less than their white counterparts. Among the six largest Asian American subgroups, research shows Asian Indian, Filipino and Vietnamese populations lose the most years of life to heart disease – up to 18 years for some – compared with white people.

The risk of early death also is high for people with a history of diabetes, stroke and heart attack. Reporting in the Journal of the American Medical Association in 2015, researchers found people with all three conditions had their life expectancy cut by 15 years compared to those without any of the health problems. Even having just two of the conditions reduced life expectancy by 12 years.

But there is hope. Continue reading

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Higher red meat eating linked with premature death – Harvard

People who increased their daily servings of red meat over an eight-year period were more likely to die during the subsequent eight years compared to people who did not increase their red meat consumption, according to a new study led by researchers from Harvard T.H. Chan School of Public Health. The study also found that decreasing red meat and simultaneously increasing healthy alternative food choices over time was associated with lower mortality.

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The study was published online June 12, 2019 in BMJ.

A large body of evidence has shown that higher consumption of red meat, especially processed red meat, is associated with higher risk of type 2 diabetes, cardiovascular disease, certain types of cancers including those of the colon and rectum, and premature death. This is the first longitudinal study to examine how changes in red meat consumption over time may influence risk of early death. Continue reading

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