Eat less; move more; live longer is the mantra of this blog. Now, it seems that our bodies are taking it upon themselves to extend our life span.
Research shows a collection of small adaptations in stress activated proteins, accumulated over millennia of human history, could help to explain our increased natural defenses and longer lifespan.
Publishing in Nature Communications, the team of collaborators from the UK, France and Finland and lead by researchers at Newcastle University, UK explain the importance of a protein called p62.
Many cells in our body, such as those which make up our brain need to last us a lifetime. To do this our cells have developed ways of protecting themselves. One way is through a process called autophagy, which literally means self-eating, where damaged components are collected together and removed from the cell.
This is very important as accumulation of damage in cells has been linked to several diseases including dementia.
Lead author, Dr Viktor Korolchuk from Newcastle University’s Institute for Ageing explains: “As we age, we accumulate damage in our cells and so it is thought that activating autophagy could help us treat older people suffering from dementia. In order to be able to do this we need to understand how we can induce this cell cleaning.”