Tag Archives: brain health

Teeth brushing may fight Alzheimer’s

As a person with no less than three cases of Alzheimer’s/dementia in his family, I have serious interest in anything relating to maintaining brain health and function. So, I was most interested in this item from the University of Bergen.

You don’t only avoid holes in your teeth by keeping good oral hygiene, researchers at the University of Bergen have discovered a clear connection between gum disease and Alzheimer’s disease.

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The researchers have determined that gum disease (gingivitis) plays a decisive role in whether a person develops Alzheimer’s or not.

“We discovered DNA-based proof that the bacteria causing gingivitis can move from the mouth to the brain,” says researcher Piotr Mydel at Broegelmanns Research Laboratory, Department of Clinical Science, University of Bergen (UiB).

The bacteria produces a protein that destroys nerve cells in the brain, which in turn leads to loss of memory and ultimately, Alzheimer’s. Continue reading

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Reaching and grasping — Learning fine motor coordination changes the brain

When we train the reaching for and grasping of objects, we also train our brain. In other words, this action brings about changes in the connections of a certain neuronal population in the red nucleus, a region of the midbrain. Researchers at the University of Basel’s Biozentrum have discovered this group of nerve cells in the red nucleus. They have also shown how fine motor tasks promote plastic reorganization of this brain region. The results of the study have been published recently in Nature Communications.

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Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan’s research group at the Biozentrum, University of Basel, has investigated the red nucleus, a region of the midbrain that controls fine motor movement, and identified a new population of nerve cells which changes when fine motor coordination is trained. The more that grasping is practiced, the more the connections between the neurons of this group of nerve cells are strengthened. Continue reading

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How to boost brain health and fight Alzheimer’s

At the risk of being repetitious, I just wanted to pass along some good information on keeping your brain intact while you are pursuing a life of healthy eating and regular exercise. That’s why you’re reading this blog, right?

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The seven guidelines to reduce risk of Alzheimer’s disease are:

  • Minimize your intake of saturated fats and trans fats. Saturated fat is found primarily in dairy products, meats, and certain oils (coconut and palm oils). Trans fats are found in many snack pastries and fried foods and are listed on labels as “partially hydrogenated oils.”
  • Eat plant-based foods. Vegetables, legumes (beans, peas, and lentils), fruits, and whole grains should replace meats and dairy products as primary staples of the diet.
  • Consume 15 milligrams of vitamin E, from foods, each day. Vitamin E should come from foods, rather than supplements. Healthful food sources of vitamin E include seeds, nuts, green leafy vegetables, and whole grains. Note: The RDA for vitamin E is 15 milligrams per day.
  • Take a B12 supplement. A reliable source of B12, such as fortified foods or a supplement providing at least the recommended daily allowance (2.4 micrograms per day for adults), should be part of your daily diet. Note: Have your blood levels of vitamin B12 checked regularly as many factors, including age, impair absorption.
  • Avoid vitamins with iron and copper. If using multivitamins, choose those without iron and copper, and consume iron supplements only when directed by your physician.
  • Choose aluminum-free products. While aluminum’s role in Alzheimer’s disease remains a matter of investigation, those who desire to minimize their exposure can avoid the use of cookware, antacids, baking powder, or other products that contain aluminum.
  • Exercise for 120 minutes each week. Include aerobic exercise in your routine, equivalent to 40 minutes of brisk walking, three times per week.

Other preventive measures, such as getting a minimum of seven hours of sleep each night and participating in 30 to 40 minutes of mental activity most days of the week, such as completing crossword puzzles, reading the newspaper, or learning a new language, can only help boost brain health.

Before you leave, just wanted to pass on a reminder about my Page – Important facts about your brain – and exercise benefits.

Tony

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What about teen cannabis use – Study

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About one in five Canadian adolescents uses cannabis (19% of Canadians aged 15-19), and its recent legalization across the country warrants investigation into the consequence of this use on the developing brain. Adolescence is associated with the maturation of cognitive functions, such as working memory, decision-making, and impulsivity control. This is a highly vulnerable period for the development of the brain as it represents a critical period wherein regulatory connection between higher-order regions of the cortex and emotional processing circuits deeper inside the brain are established. It is a period of strong remodeling, making adolescents highly vulnerable to drug-related developmental disturbances. Research presented by Canadian neuroscientists Patricia Conrod, Steven Laviolette, Iris Balodis and Jibran Khokhar at the 2019 Canadian Neuroscience Meeting in Toronto on May 25 featured recent discoveries on the effects of cannabis on the adolescent brain.

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Researchers Define Alzheimer’s-like Brain Disorder

As regular readers know, I have a history of Alzheimer’s Disease or some form of dementia on both sides of my family, so I entertain a strong interest in the subject, particularly since I am a senior citizen.

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A brain disorder that mimics symptoms of Alzheimer’s disease has been defined with recommended diagnostic criteria and guidelines for advancing future research on the condition. Researchers at Rush University Medical Center and scientists from several National Institutes of Health-funded institutions, in collaboration with international peers, described the newly named pathway to dementia, limbic-predominant age-related TDP-43 encephalopathy, or LATE, in a report published today in the journal Brain.

“We proposed a new name to increase recognition and research for this common cause of dementia, the symptoms of which mimic Alzheimer’s dementia but is not caused by plaques and tangles (the buildup of beta amyloid proteins that Alzheimer’s produces). Rather, LATE dementia is caused by deposits of a protein called TDP-43 in the brain,” said Dr. Julie Schneider, senior author of the Brain paper and associate director of the Rush Alzheimer’s Disease Center. Continue reading

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Tufts on brain food

The science of whether some dietary choices can be considered brain food or not continues to unfold.

Given long time-frames of conditions such as Alzheimer’s disease and other dementias, it’s challenging to prove any cause and effect relationship between specific foods and brain health. Most such associations are drawn from observational studies, in which people who eat more or less of a certain food are assessed over time for cognitive changes.

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It’s obviously difficult to feed a group of study participants lots of, say, blueberries for several years in order to test their brain health at the end; that’s why clinical trials of so-called brain foods have largely depended on animal tests.

Nonetheless, some foods tend to stand out from the pages and pages of research results as most likely being protective for brain health. Continue reading

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Is it possible to supercharge memories back to life? – BU Study

As a 79 year old bike rider, I know how much I am counting on exercise to keep my brain intact as I age. So, I was nothing less than amazed to run across the Boston University (BU) study on electrically stimulating brain function in seniors.

BU brain scientist shows electrostimulation can restore a 70-year-old’s working memory to that of a 20-year-old.

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As you read the words stretched across this page, your brain is doing something magnificent. Each sentence lingers in your mind for a fleeting moment, the letters melding into a symphony of neural signals. These intricate electrical rhythms form the language of the brain, a language we have only begun to understand within the last century.

Rob Reinhart, an assistant professor of psychological and brain sciences at Boston University, says we’ve reached a point where we not only understand this language—we can speak it and harness it to enhance the functioning of the mind. In a groundbreaking study published April 2019 in Nature Neuroscience, Reinhart and BU doctoral researcher John Nguyen demonstrate that electrostimulation can improve the working memory of people in their 70s so that their performance on memory tasks is indistinguishable from that of 20-year-olds.

Reinhart and Nguyen’s research targets working memory—the part of the mind where consciousness lives, the part that is active whenever we make decisions, reason, recall our grocery lists, and (hopefully) remember where we left our keys. Working memory starts to decline in our late 20s and early 30s, Reinhart explains, as certain areas of the brain gradually become disconnected and uncoordinated. By the time we reach our 60s and 70s, these neural circuits have deteriorated enough that many of us experience noticeable cognitive difficulties, even in the absence of dementias like Alzheimer’s disease. Continue reading

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Brain health connects to heart health – CDC

Eat less; move more; live longer is the mantra here. Apparently, it also leads to think better, too. The Centers for Disease Control and Prevention (CDC) seems to think so.

Did you know that the health of your brain and your heart are connected? By keeping your heart healthy, you also lower your risk for brain problems such as stroke and dementia. Learn more about the connection between the heart and brain and steps to take to keep both healthy.

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Heart disease, stroke, and vascular dementia are preventable. Take steps to reduce your risk.

 

  • Control your blood pressure. High blood pressure is a leading cause of heart disease and stroke. Over time, high blood pressure puts too much stress on blood vessels. Scientists now know that having uncontrolled high blood pressure in midlife also raises your risk for dementia later in life. Know your numbers by getting your blood pressure checked regularly. If your blood pressure is high, work with your doctor, nurse, or health care team to manage it. One way to manage your blood pressure is to take your medicines as prescribed. Learn more ways to manage blood pressure.
  • Eat healthy foods and limit alcohol. Eat plenty of vegetables, fruits, whole grains, and low-fat dairy, and include seafood rich in omega-3 fatty acids (such as salmon) each week. Limit foods with added sugars and saturated fats, and lower your sodium (salt) intake. If you drink alcohol, drink in moderation. Drinking too much alcohol raises blood pressure, which can lead to stroke and increase the risk of some kinds of heart disease.
  • Get diabetes under control. Diabetes causes high blood sugar, which can damage blood vessels and nerves. This damage raises the risk for heart disease, stroke, and dementia.
  • Don’t smoke. Smoking damages blood vessels and makes blood more likely to clot, which can lead to heart disease and stroke. Smoking is the leading cause of preventable death in the United States. If you don’t smoke, don’t start. If you do smoke, learn how to quit.
  • Stay active. Lack of physical activity can lead to high blood pressure and obesity. Most Americans don’t meet guidelines of getting at least 150 minutes of moderate-intensity exercise each week. Find ways to get your heart pumping for at least 150 minutes per week. Take the stairs, schedule a walk at lunch, or do jumping jacks during commercial breaks. Learn more about how to get enough physical activity.

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Neuroplasticity – one brainy word

Since I had that nice infographic on the brain yesterday, I thought this one on brain function might be a useful follow-up.

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If you are interested in reading more about that wonderful organ inside your head, feel free to check out my Page – Important facts about your brain (and exercise benefits)

Tony

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Thinking about your brain – infographic

I love this infographic of the brain. Surprisingly, they left out one of the most impressive facts to me, namely, that the brain burns 20 to 25 percent of our daily calories. Bigger than any single muscle.

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Before you go, please check out my Page – Important facts about your brain (and exercise benefits) for a lot more details on this major organ in our body.

Tony

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Keeping active in middle age may be tied to lower risk of dementia – Study

In the nearly 10 years of writing this blog I have come to believe that use it or lose it is an unassailable law of the body. And what applies to the body often carries over to the brain. As I have mentioned previously, my family has dementia in general and Alzheimer’s in particular on both sides, so keeping a clear head really resonates with me.

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My dog and me out for a ride. I am a little past middle age in the picture, but you get the idea.

Keeping physically and mentally active in middle age may be tied to a lower risk of developing dementia decades later, according to a study published in the medical journal Neurology. Mental activities included reading, playing instruments, singing in a choir, visiting concerts, gardening, doing needlework or attending religious services.

“These results indicate that these activities in middle age may play a role in preventing dementia in old age and preserving cognitive health,” said study author Jenna Najar, MD, from Sahlgrenska Academy, University of Gothenburg.

“It’s exciting as these are activities that people can incorporate into their lives pretty easily and without a lot of expense.” Continue reading

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5 Daily ways to brain and heart health

I know this looks utterly simple, but sometimes we overlook the simplest things/ideas that could be very helpful to us.  Please take a minute to go over this and ensure that you are, in fact, doing them.

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Emergency and Urgent Hospitalizations Linked to Accelerated Cognitive Decline in Seniors

My interest in cognition and cognitive decline, particularly in seniors brought me to this amazing study. I think it may give further import to the idea of maintaining a physically  active life into our senior years,

Emergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at Rush University Medical Center. Results of their study, published in the Jan. 11, 2019, online issue of Neurology shows that hospitalization may be a more of a major risk factor for long-term cognitive decline in older adults than previously recognized.

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“We found that those who have non-elective (emergency or urgent) hospitalizations and who have not previously been diagnosed with dementia or Alzheimer’s disease had a rapid decline in cognitive function (i.e., thinking abilities) compared to the pre-hospital rates,” said Bryan James, PhD, an epidemiologist and in the Rush Alzheimer’s Disease Center and an assistant professor in the Rush Department of Internal Medicine. “By comparison, people who were never hospitalized and those who had elective hospitalizations did not experience the drastic decline in cognitive function.” Continue reading

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Social Exclusion Spurs Extremism in Those Vulnerable to Radicalization – Study

Summary: A neuroimaging study reveals the effects of social exclusion in the left inferior frontal gyrus. The study found social exclusion can spur extremist behaviors in people who are most vulnerable to radicalization. Source: Universitat Autònoma de Barcelona.

A study led by researchers from the Universitat Autònoma de Barcelona (UAB) and the Hospital del Mar Medical Research Institute (IMIM), in collaboration with other international institutions, explored the neural and behavioral relationships between sacred values, violent extremism and social exclusion in a group of young Moroccan men living and schooled in Catalonia and vulnerable to radicalization.

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A study conducted by the UAB and IMIM used neuroimaging techniques to show that social exclusion increases the number of ideological and group values worth fighting and dying for in populations vulnerable to radicalisation. The study focused on neural activity in a region of the brain related to rule retrieval and sacred values. NeuroscienceNews.com image is in the public domain.Sacred values are those perceived as non-negotiable, those which must be upheld at all costs. They also contain an identity component related to perceiving the person as a member of their reference group.

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Number of People with Dementia Has Doubled in Sixteen Years

The number of people living with dementia globally more than doubled between 1990 and 2016 from 20.2 million to 43.8 million, prompting researchers to call for more preventative action.

A new paper published in The Lancet Neurology also found that 22.3 per cent of healthy years lost due to dementia in 2016 were due to modifiable risk factors.

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Prepared by academics across multiple institutions and led by the University of Melbourne and the University of Washington, the paper looked at the global, regional and national burden of Alzheimer’s Disease and other dementias from 1990-2016.

The systematic analysis of the Global Burden of Disease Study 2016 found dementia was more common at older ages, with the prevalence doubling every five years over age 50. There was also significant potential for prevention.

“In our study, 22.3 per cent (11.8 – 35.1 per cent) of the total global disability-adjusted life years lost due to dementia in 2016 could be attributed to the four modifiable risk factors – being overweight, high blood sugar, consuming a lot of sugar sweetened beverages and smoking,” the authors said.

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Regular exercise changes the brain – Harvard

Eat less; move more; live longer remains the mantra of this blog. It is good to learn from Harvard, no less, that moving more also helps to keep our brain intact and functioning.

There are plenty of good reasons to be physically active. Big ones include reducing the odds of developing heart disease, stroke, and diabetes. Maybe you want to lose weight, lower your blood pressure, prevent depression, or just look better. Here’s another one, which especially applies to those of us (including me) experiencing the brain fog that comes with age: exercise changes the brain in ways that protect memory and thinking skills.

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In a study done at the University of British Columbia, researchers found that regular aerobic exercise, the kind that gets your heart and your sweat glands pumping, appears to boost the size of the hippocampus, the brain area involved in verbal memory and learning. Resistance training, balance and muscle toning exercises did not have the same results.

The finding comes at a critical time. Researchers say one new case of dementia is detected every four seconds globally. They estimate that by the year 2050, more than 115 million people will have dementia worldwide. Continue reading

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