Tag Archives: brain

Cholesterol levels linked Alzheimer’s – MNT

I have mentioned previously about losing three family members to Alzheimer’s Disease and/or dementia. Hence, my own serious concern about these mental conditions. I remember my aunt whom Alzheimer’s took had very high cholesterol late in life and had been warned by her doctor that she needed to get her numbers down. So, this study from  Medical News Today published several years ago had real meaning for me.

aHR0cDovL3d3dy5saXZlc2NpZW5jZS5jb20vaW1hZ2VzL2kvMDAwLzA4NS81NTcvb3JpZ2luYWwvYnJhaW4tbmV1cm9ucy5qcGc=.jpeg

Project leader Bruce Reed, a professor of neurology at the University of California (UC) Davis, and associate director of its Alzheimer’s Disease Center, says:

“Our study shows that both higher levels of HDL – good – and lower levels of LDL – bad – cholesterol in the bloodstream are associated with lower levels of amyloid plaque deposits in the brain.”

Continue reading

Advertisements

3 Comments

Filed under aging brain, Alzheimer's disease, brain, brain function, brain health, cholesterol, HDL Cholesterol, LDL Cholesterol

7 steps for brain health from childhood to old age – AHA

The American Heart Association (AHA) has a superb rundown on the benefits of a healthy lifestyle, literally from cradle to grave. I can’t tell you how gratifying it is to see these concepts broadcast by the mainstream health outlets like the AHA. The following is directly from them. At the end I have listed some of my posts which flesh out these steps. Remember, eat less; move more; live longer.

A healthy lifestyle benefits your brain as much as the rest of your body — and may lessen the risk of cognitive decline (a loss of the ability to think well) as you age, according to a new advisory from the American Heart Association/American Stroke Association.

 

c80992a1012118373be3f673cecdf16bf4f6c32b_original

Both the heart and brain need adequate blood flow, but in many people, blood vessels slowly become narrowed or blocked over the course of their life, a disease process known as atherosclerosis, the cause of many heart attacks and strokes. Many risk factors for atherosclerosis can be modified by following a healthy diet, getting enough physical activity, avoiding tobacco products and other strategies.

“Research summarized in the advisory convincingly demonstrates that the same risk factors that cause atherosclerosis, are also major contributors to late-life cognitive impairment and Alzheimer’s disease. By following seven simple steps — Life’s Simple 7 — not only can we prevent heart attack and stroke, we may also be able to prevent cognitive impairment,” said vascular neurologist Philip Gorelick, M.D., M.P.H., the chair of the advisory’s writing group and executive medical director of Mercy Health Hauenstein Neurosciences in Grand Rapids, Michigan.

Continue reading

1 Comment

Filed under aging brain, brain, brain function, brain health, Exercise, exercise and brain health, exercise benefits, smoking, Smoking dangers

How avocados and nuts could boost intelligence – MNT

Here is some heartening news for folks worried about fats consumption.

You may want to think about adding avocados, olive oil, and nuts to your grocery list, since a new study has suggested that the monounsaturated fatty acids in these foods could boost intelligence.

incorporating-nuts-seeds-oil-in-mediterranean-diet.jpg

Researchers from the University of Illinois at Urbana-Champaign found that higher levels of monounsaturated fatty acids (MUFAs) in the blood correlated with greater general intelligence in older adults.

Study leader Aron K. Barbey, a professor of psychology at the university, and colleagues recently reported their results in the journal Neuroimage.

Continue reading

Leave a comment

Filed under aging brain, avocados, brain, brain function, brain health, guide to health benefits of edible seeds, nuts

Brain activity may predict stress-related cardiovascular risk – AHA

I have written numerous posts on the brain, stress and relaxation. This study seems to be an amalgam of them all. If you want to read further on any of them, punch the word into the S E A R C H box at the right and have at it. There is a lot of information available.

  • A pattern of brain activity that occurs during psychological stress may predict bodily reactions, such as surges in our blood pressure, that increase risk for cardiovascular disease.
  • People who have exaggerated responses to stressors, like large rises in blood pressure or heart rate, are at greater risk of developing hypertension and premature death from cardiovascular disease, researchers say.

2-brain

The brain may have a distinctive activity pattern during stressful events that predicts bodily reactions, such as rises in blood pressure that increase risk for cardiovascular disease, according to new proof-of-concept research in the Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association. Continue reading

2 Comments

Filed under aging brain, American Heart Association, brain, brain damage, brain function, brain health, dealing with stress, stress, stress reduction

When writing interferes with hearing – Study

This is a little off the beaten path for me, but I thought any information on brain function is useful information. The following is from Science Daily.

A cochlear implant is an electronic device capable of restoring hearing in a profoundly deaf person by directly stimulating the nerve endings in the inner ear. This technology enables people who have become deaf to be able to communicate orally again, even by telephone, and children born deaf to learn to speak and to benefit from normal schooling. However, results can be extremely variable, with implants having only little benefit for some patients, without any means of predicting failure based only on purely clinical factors. Using data from brain imaging techniques that enable visualizing the brain’s activity, a neuroscientist at the University of Geneva (UNIGE) and a Parisian ENT surgeon have managed to decipher brain reorganization processes at work when people start to lose their hearing, and thus predict the success or failure of a cochlear implant among people who have become profoundly deaf in their adult life. The results of this research may be found in Nature Communications.

Up, red: right occipito-temporal coupling during deafness, indicating a poor cochlear implant prognosis. Below, blue: right occipito-tempora uncoupling after deafness, indicating a good cochlear implant outcome (adapted from Strelnikov et al. 2013).
Credit: © UNIGE – Institut Vernes, Paris

Continue reading

Leave a comment

Filed under brain, brain function, brain health, hearing

Your brain on chocolate – Harvard

At the risk of repeating myself yet again, my family has a history of Alzheimer’s and dementia, so any info on brain health resonates deeply with me.

Here is Dr. Robert H. Shmerling, Faculty Editor, Harvard Health Publications on chocolate and your brain.

100915_fobette-main

Did you know that places where chocolate consumption is highest have the most Nobel Prize recipients? It’s true, at least according to a 2012 study published in the New England Journal of Medicine. Of course, that could be a coincidence. But is it possible that intelligence or other measures of high brain function are actually improved by the consumption of chocolate? A new review summarizes the evidence and concludes with a resounding “maybe.”

Keeping your brain healthy

When it comes to preserving and improving brain function, let’s face it: we need all the help we can get. With age, diseases that cause dementia, such as stroke, Alzheimer’s disease, and Parkinson’s disease, become more common. And since we have an aging population, predictions are that dementia will become much more common in the near future. Yet despite decades of research, there are no highly effective treatments for dementia. Continue reading

3 Comments

Filed under aging brain, brain, brain function, brain health, chocolate, Harvard Health Publications, Healthy brain

Reaction time variation may predict mortality in old age – Study

A common indicator of neurobiological disturbance among the elderly may also be associated with mortality, according to a study published August 9, 2017 in the open access journal PLOS ONE by Nicole A. Kochan at the Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney.

2-brain

Intraindividual reaction time variability (IIVRT), defined as an individual’s variation in reaction times when completing a single cognitive task across several trials, has been associated with mild cognitive decline, dementia and Parkinson’s disease. The authors of this study investigated whether IIVRT is also associated with mortality in old age by following a cohort of 861 adults aged 70 years to 90 years over an eight-year period.

Kochan and colleagues tested the participants’ baseline reaction time by having them complete two brief computerized cognitive tasks comprising 76 trials to measure the average reaction time and the extent of variation over the trials. Every two years, research psychologists followed up on the participants and conducted a comprehensive medical assessment including a battery of neuropsychological tests to assess the participants’ cognitive function. Cases were also reviewed by a panel of experts to determine a dementia diagnosis in each two year follow-up, and mortality data was collected from the state registry.

Study results indicate that greater IIVRT predicted all-cause mortality, but the average RT did not predict time to death. Researchers found that other risks factors associated with mortality such as dementia, cardiovascular risk and age could not explain the association between IIVRT and mortality prediction. The authors suggested that IIVRT could therefore be an independent predictor of shorter time death.

“The study was the first to comprehensively account for effects of overall cognitive level and dementia on the relationship between intraindividual variability of reaction time and mortality,” says Kochan. “Our findings suggest that greater intraindividual reaction time variability is a behavioural marker that uniquely predicts shorter time to death.”

Leave a comment

Filed under aging, aging brain, brain, brain function, brain health, living longer, longevity, successful aging

To what extent is dementia preventable?

Regular readers know that my family has a history of Alzheimer’s Disease and/or dementia. This is true on both my mother’s and father’s side. So, at 77, I am totally focused on anything that relates to these mental conditions. The following is from the Keck School of Medicine at USC by Erica Rheinschild.

Experts say that one-third of the world’s dementia cases could be prevented by managing lifestyle factors such as hearing loss, hypertension and depression.

 

17-07-2046-Dementia-IG_Final_2-768x576.jpg

This remarkable fact was part of a report by the first Lancet Commission on Dementia Prevention and Care that was presented at the Alzheimer’s Association International Conference (AAIC) 2017 and published in The Lancet. The report also highlighted the beneficial effects of nonpharmacologic interventions such as social contact and exercise for people with dementia. Continue reading

Leave a comment

Filed under aging, aging brain, Alzheimer's, Alzheimer's disease, Alzheimer's risk, cardio exercise, dementia, Exercise, exercise benefits, successful aging

Older brains benefit from all types of exercise

At the risk of being repetitious, I have had three family members suffer from Alzheimer’s Disease and/or dementia. At the age of 77 I am really concerned about living a long life, but WITH my brain fully functional. That is only one of the reasons I ride my bike every day here in Chicago. I promote exercise in all its forms here and subscribe to the mantra: eat less; move more; live longer.

Brain

Brain

Many studies have told us exercise is good for the brain. But does it depend on the type of exercise? New research suggests not – at least for seniors. A study of older people found the brain benefits from many types of physical activities – and you don’t have to go to the gym to do them, according to Medical News Today.

The team, from the Institut universitaire de gériatrie de Montréal, an institution affiliated with the University of Montreal in Canada, reports the findings in the journal AGE. Continue reading

4 Comments

Filed under aging brain, Alzheimer's disease, brain, brain function, brain health, dementia, exercise and brain health

Can too much sitting erase exercise benefits?

I have written about the dangers of prolonged sitting previously. You can check out my Page – Do you know the dangers of too much sitting?  for further information on it.

White matter is brain tissue containing nerve fibers responsible for brain communication. As we age, nerve fiber activity declines and disrupts brain function. But a new study suggests that among older adults, the structural integrity of white matter is not only dependent on levels of physical activity, but also on the amount of remaining time spent sedentary, according to Medical News Today.

the_evil_chair1.jpg

Lead researcher Agnieszka Burzynska, a postdoctoral researcher at the University of Illinois, and her team publish their findings in the journal PLOS ONE.

Past studies have associated physical activity among older adults with reduced cognitive decline. In 2012, research from the University of Scotland in the UK found that seniors who had high levels of physical activity had fewer problems with memory and thinking skills, while a 2013 study claimed exercise is beneficial for the cognitive functioning of dementia patients. Continue reading

1 Comment

Filed under brain, brain damage, brain function, Exercise, prolonged sitting, sitting, sitting too long

Could changes in thinking skills be reversible dementia? – Harvard

Regular readers know that I have had a number of Alzheimer’s and dementia occurrences in my immediate family. So, I am especially sensitive to anything related to dementia. The following is from Heidi Godman, Exetutive Editor, Harvard Health Letter.

We use the term “dementia” to describe a number of conditions that cause permanent thinking skills changes, such as memory loss and confusion. The most common kind of dementia is Alzheimer’s disease, which is characterized by clumping proteins that get tangled in and around brain cells, eventually causing them to die. The second most common type of dementia is vascular dementia, caused by decreased blood flow to the brain from atherosclerosis—the accumulation of fatty deposits on artery walls.

c80992a1012118373be3f673cecdf16bf4f6c32b_original

Once dementia strikes, the damage is permanent, and we don’t have many treatment options. So, before a diagnosis is made, it’s crucial to rule out whether the causes for dementia are actually reversible conditions. Continue reading

2 Comments

Filed under aging brain, Alzheimer's, Alzheimer's disease, Alzheimer's risk, brain, brain function, brain health, dementia

Cholesterol may affect brain functions – Study

Having lost three family members to Alzheimer’s Disease and dementia, I was fascinated by this information from researchers in Berlin.

A study led by researchers at the Hospital del Mar Medical Research Institute (IMIM) and the Institute of Medical Physics and Biophysics at the Faculty of Medicine in Charité Hospital, Berlin, published in the journal Nature Communications, demonstrates that the cholesterol present in cell membranes can interfere with the function of an important brain membrane protein, through a previously unknown mode of interaction. Specifically, cholesterol is capable of regulating the activity of the adenosine receptor, by invading it and accessing the active site. This will allow new ways of interacting with these proteins to be devised that in the future could lead to drugs for treating diseases like Alzheimer’s.

2-brain

The adenosine receptor belongs to the GPCR family (G Protein-Coupled Receptors), a large group of proteins located in cell membranes, which are key in the transmission of signals and communication between cells. GPCRs are therefore involved in the majority of important physiological processes, including the interpretation of sensory stimuli such as vision, smell, and taste, the regulation of the immune and inflammatory system, and behavior modulation. Continue reading

Leave a comment

Filed under aging brain, Alzheimer's disease, brain, brain function, cholesterol, dementia

What does it take to be a super-ager? – Harvard

One of the stated aims of this blog is to live past 100. Posts every day touch on that goal, but mostly in a ‘part of the big picture’ way. Herewith some positive ideas from Harvard Health publications directly on the subject of super-aging.

Finding role models who are older than we are gets more difficult as we age. But in the last few years, medical science has identified a new group we can aspire to join — the super-agers. The term refers to people in their 70s and 80s who have the mental or physical capability of their decades-younger counterparts.

c80992a1012118373be3f673cecdf16bf4f6c32b_original

Although super-agers’ brains show less cell loss than those of their contemporaries, their IQs and educational levels are similar. What sets them apart might be that they view problem-solving differently, Dr. Dickerson says. “They may approach these tasks as a challenge they can succeed at, in contrast to typical older adults who may give up.” Continue reading

1 Comment

Filed under cardio exercise, Exercise, exercise and brain health, exercise benefits, Harvard, Harvard Health Publications, Harvard Medical School, super-ager

Sweet or savory? Research on how the brain makes preference-based decisions

Some like it hot, but most folks choose sweet or savory ahead of it.

Researchers have found a direct window into the brain systems involved in making every day decisions based on preference.

The study, led by a team of neuroscientists at the University of Glasgow’s Institute of Neuroscience and Psychology, and published in Nature Communications, offers crucial insight into the neural mechanisms underlying our decision-making process, opening up new avenues for the investigation of preference-based choices in humans.

Sweet-vs-Savory-Popcorn.jpg

Whether we decide to opt for a piece of apple or a piece of cake is, for example, a preference-based decision. How our brains arrive at such decisions – as well as choices that rely on our subjective valuation of different alternatives – is currently a popular research topic. Continue reading

Leave a comment

Filed under brain, brain function, sweet or savory

Dining hall intervention helped students’ choices

As I have written in some of my blog posts on the brain. It is our frontal lobes that separate us from the rest of the creatures on this earth. That’s where our conscience resides and our decision-making takes place – our impulse control. It is a fact that the frontal lobes are the last to develop, often times this part of the brain is not developed until the individual reaches age 25. Personally, I found this fact to be an excellent explanation of why I made some of the really dangerous choices I did as a teen. It is well to keep this slow development fact in mind when thinking about freshmen in college living away from home for the first time in their lives.

As students transition from high school to college, they enter a critical period for weight gain. Although eating in a buffet-style dining hall offers freedom and flexibility in food choice, many students cite the abundance of food available as a cause for weight gain. As most college students’ diets are low in fruits and vegetables and high in calories, sugar, fat, and sodium, researchers from the University of Toronto and Memorial University of Newfoundland created a cross-sectional study to examine whether messaging encouraging fruit, vegetable, and water intake could influence the habits of university students.

Greendale_cafeteria.png

“Our labeling, focused on beverages and fruits and vegetables, may have been useful to decrease students’ consumption of sugar-sweetened beverages and increase consumption of , fruits, and vegetables,” said lead author Mary Scourboutakos, PhD, post-doctoral researcher at the University of Toronto. Continue reading

Leave a comment

Filed under brain, brain function, brain health, Healthy brain, healthy eating

7 Simple suggestions to live longer – AHA

Living past 100 is no walk in the park, although including one can prove very helpful. The American Heart Association has created this list with the goal of improved health by educating the public on how best to live longer and healthier.

These measures have one unique thing in common: any person can make these changes, the steps are not expensive to take and even modest improvements to your health will make a big difference. Start with one or two. This simple, seven step list has been developed to deliver on the hope we all have–to live a long, productive healthy life. 

xheart-health.jpg.pagespeed.ic.1pedeecgyj

Manage Blood Pressure
High blood pressure is a major risk factor for heart disease and stroke. When your blood pressure stays within healthy ranges, you reduce the strain on your heart, arteries, and kidneys which keeps you healthier longer.
Learn how to manage your blood pressure. Continue reading

Leave a comment

Filed under American Heart Association, Exercise, exercise benefits, living longer, longevity, smoking, Smoking dangers