Vitamin D deficiency is associated with an increased risk of developing bladder cancer, according to a systematic review of seven studies led at the University of Warwick.
Five out of the seven studies linked low vitamin D levels to an increased risk of bladder cancer.
The researchers then looked at the cells that line the bladder, known as transitional epithelial cells, and found that these cells are able to activate and respond to vitamin D, which in turn can stimulate an immune response.
This is important because the immune system may have a role in cancer prevention by identifying abnormal cells before they develop into cancer. Lead author of the study Dr. Rosemary Bland said, “More clinical studies are required to test this association, but our work suggests that low levels of vitamin D in the blood may prevent the cells within the bladder from stimulating an adequate response to abnormal cells. Continue reading