Category Archives: Alzheimer’s disease

Healthy eating may reduce risk of dementia – AAIC Conference

Because of the Alzheimer’s Disease and dementia in my family, I have been an avid student of ways to protect myself as I age. Check out my Page – Important facts about your brain (and exercise benefits) for more. Regarding our general physical health I know that diet contributes about 70 percent and exercise 30 percent. It turns out that diet also provides important elements of brain health, too.

Results from four large population-based studies support a connection between good dietary practices and better cognition in old age. Study results were reported at the 2017 Alzheimer’s Association International Conference (AAIC 2017) in London.

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A group of U.S. scientists found that, among nearly 6,000 older adults in the Health and Retirement Study, those who consistently followed diets long known to contribute to cardiovascular health were also more likely to maintain strong cognitive function in old age. They found that sticking to the specially designed MIND diet and Mediterranean diet was associated with 30 to 35 percent lower risk of cognitive impairment in healthy older adults. In fact, the investigators discovered that those with healthier diets exhibited meaningful preservation of cognitive function.

  • The Mediterranean and DASH (Dietary Approaches to Stop Hypertension) diets were originally developed or codified to help improve cardiovascular health.
  • A hybrid of these diets, called the Mediterranean-DASH Intervention for Neurodegenerative Delay, or MIND diet, is gaining attention for its potential positive effects on preserving cognitive function and reducing dementia risk in older individuals. A 2015 study found that individuals adhering to this diet exhibited less cognitive decline as they aged (Morris et al. Alzheimer’s Dement. 2015; 11:1015-22).

Other diet-related studies reported at AAIC 2017 included:

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Cholesterol may affect brain functions – Study

Having lost three family members to Alzheimer’s Disease and dementia, I was fascinated by this information from researchers in Berlin.

A study led by researchers at the Hospital del Mar Medical Research Institute (IMIM) and the Institute of Medical Physics and Biophysics at the Faculty of Medicine in Charité Hospital, Berlin, published in the journal Nature Communications, demonstrates that the cholesterol present in cell membranes can interfere with the function of an important brain membrane protein, through a previously unknown mode of interaction. Specifically, cholesterol is capable of regulating the activity of the adenosine receptor, by invading it and accessing the active site. This will allow new ways of interacting with these proteins to be devised that in the future could lead to drugs for treating diseases like Alzheimer’s.

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The adenosine receptor belongs to the GPCR family (G Protein-Coupled Receptors), a large group of proteins located in cell membranes, which are key in the transmission of signals and communication between cells. GPCRs are therefore involved in the majority of important physiological processes, including the interpretation of sensory stimuli such as vision, smell, and taste, the regulation of the immune and inflammatory system, and behavior modulation. Continue reading

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15 health benefits of pomegranate juice

I have to confess a great deal of ignorance when it comes to the pomegranate. I haven’t had one in years. I have had some of the juice the comes in very cool shaped bottles.

Today, pomegranate juice is being studied for its many health benefits. It may help with cancer prevention, immune support, and fertility.

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Here are some of the potential benefits of pomegranate, according to Medical News Today.

1. Antioxidants

Pomegranate seeds get their vibrant red hue from polyphenols. These chemicals are powerful antioxidants.

Pomegranate juice contains higher levels of antioxidants than most other fruit juices. It also has three times more antioxidants than red wine and green tea. The antioxidants in pomegranate juice can help remove free radicals, protect cells from damage, and reduce inflammation.

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Tea drinking may help prevent dementia – Harvard

Good news for tea drinkers or all stripes. A study in the December 2016 Journal of Nutrition, Health & Aging showed that drinking tea frequently is associated with a lower risk of dementia, especially for people who are genetically predisposed to the disease, Harvard Men’s Health Watch reported.

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Researchers followed 957 older adults, average age 65, who were part of the Singapore Longitudinal Aging Study. Of these, 69% drank tea on a frequent basis. After a five-year period, the researchers found that the tea drinkers had a 50% lower risk of dementia. This is consistent with earlier findings that showed tea consumers scored higher on various cognitive tests.

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Extra-virgin olive oil may prevent Alzheimer’s

New research suggests that extra-virgin olive oil – a key component of the Mediterranean diet – may protect the brain from Alzheimer’s disease symptoms. Mouse experiments revealed changes in both cognitive performance and the appearance of nerve cells.

Alzheimer’s disease is estimated to affect approximately 5 million people in the United States. The neurodegenerative disease is progressive and cannot yet be cured or reversed.

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But new research moves closer to a prevention – and potentially reversing – strategy, by studying the effects of extra-virgin olive oil on the cognitive performance and brain health of mice.

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Can Exercise Slow Cognitive Decline?

Experts in aging and Alzheimer’s disease are conducting a national clinical study to determine if exercise may be an effective non-drug intervention for maintaining cognitive fitness.

The Rush Alzheimer’s Disease Center at Rush University Medical Center is the only site in Illinois, and one of only 15 sites across the United States leading the Exercise in Adults With Mild Memory Problems (EXERT) study, which is trying to determine if exercise can slow the progress of memory loss and cognitive impairment in older adults.

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Neuroscientists are collaborating with the YMCA to provide individualized, one-on-one exercise programs and personal training to study participants. Rush will be working with the McGaw YMCA in Evanston, Illinois, to provide 45-minute personal training sessions for one year.

Adults with memory issues may avoid being active when they need it most

“We want to see if a personalized program implemented in the community and prescribed by health care providers can be an effective therapy for people with memory issues,” said Dr. Neelum Aggarwal, associate professor of neurology and principal investigator of the EXERT study at Rush. Continue reading

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Genes Associated With Resilience Against Brain Pathology Identified

Having had three family members who suffered from some form of dementia I am highly motivated to find out all I can about this scourge that devastates mostly seniors. The following is from the Rush Alzheimer’s Disease Center.
Genes help cognition withstand damage in brain from Alzheimer’s, Parkinson’s

The pathologies (damage) in the brain that stroke, Alzheimer’s disease and other neurological conditions cause in older adults only partially explain the memory loss, reduced reasoning ability and other cognitive impairments that result from these conditions. Little is known about why the effects of brain pathology vary between people who develop it.

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Now researchers have discovered two genes, known as UNC5C and ENC1, that are associated with aging individuals having better memory and brain function than would be expected, given the amount of pathologies that accumulated in their brains. They reported their findings in an article published today in the journal PLOS Medicine. Continue reading

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Brain’s Power to Adapt Offers Short-Term Gains, Long-Term Strains

There is not necessarily fresh ground broken here, but I think seeing details on how the brain functions can only be helpful. The most important idea for me is one I had going in, namely, you only have one brain so take care of it.

Like air-traffic controllers scrambling to reconnect flights when a major hub goes down, the brain has a remarkable ability to rewire itself after suffering an injury. However, maintaining these new connections between brain regions can strain the brain’s resources, which can lead to serious problems later, including Alzheimer’s Disease, according to researchers.

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After a head injury, the brain can show enhanced connectivity by using alternative routes between two previously connected regions of the brain that need to communicate, as well as make stronger connections, said Frank G. Hillary, associate professor of psychology, Penn State. These new connections between damaged areas are often referred to as hyperconnections, he added. Continue reading

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Can gut bacteria affect Alzheimer’s?

As a person who has lost three family members to dementia or Alzheimer’s Disease, this new information on the subject knocked me out.

Please see my Page – Important facts about your brain (and exercise benefits) for more.

Tony

New research finds the microbes in your gut may play a major role in escalating the chronic brain disease. A raft of recent studies has shown that the microbiome is a factor in the development of obesity, type 2 diabetes, asthma, and cardiovascular disease. Now, we can add Alzheimer’s disease to the list. A new […]

via Can Gut Bacteria Affect Alzheimer’s Disease? — Our Better Health

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Can exercise help people at risk for Alzheimer’s – Study

One of the main goals in living longer is having one’s brain fully functional. Since I have both Alzheimer’s and dementia in my family tree, I am totally focused on keeping my brain working. There is no question that exercise can help one defend against dementia, but with Alzheimer’s the jury is still out.

Can exercise slow or prevent cognitive decline in older people who are at increased risk for Alzheimer’s disease? A new clinical trial led by National Institute on Aging (NIA) -supported scientists in collaboration with the YMCA aims to find out whether exercise may be an effective nondrug treatment for staying cognitively fit.

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The trial, called EXERT, will enroll 300 people, age 65 to 89, with mild cognitive impairment (MCI), a condition of mild memory problems that often leads to Alzheimer’s dementia. Based on the trial’s results, the researchers hope to develop an evidence-based “prescription” that will tell people the type and frequency of exercise needed to support memory and thinking skills.

“We want to design a real-life program that can be implemented in the community and prescribed by healthcare providers,” said Laura D. Baker, Ph.D., of Wake Forest Baptist Medical Center in Winston-Salem, N.C., who is leading the study with Carl W. Cotman, Ph.D., of the University of California, Irvine.

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Women perform better than men on memory tests for Alzheimer’s

Since I have at least three cases of Alzheimer’s or dementia in my family, this kind of information always resonates with me.

Women do better on verbal memory tests commonly used to diagnose Alzheimer’s disease compared to men with the same amount of neurotoxic protein in their brains, a new study has found.

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It is well known that females have an advantage on verbal memory tests, in which subjects are challenged to recite back a list of heard words. Because women are better at the tests, which are often used to help detect and diagnose Alzheimer’s disease, the severity of their disease may be missed, says Dr. Pauline Maki, professor of psychiatry and psychology at the University of Illinois at Chicago and an author on the study, published in the Journal of Alzheimer’s Disease.

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High cholesterol intake and eggs do not increase risk of memory disorders

I am now and  have been for years a big fan of eggs. A hundred years ago, it seems, I worked on the Chicago Mercantile Exchange trading floor where I covered the egg futures market along with pork bellies, live cattle and live hog futures. In that capacity, I learned a great deal about eggs from their production to our consumption. I have posted on them numerous times. Here are a few: Eating eggs is good for you. I wrote that in the first month of this blog’s existence. Feel free to type e-g-g-s in the search box at the right to read more posts on eggs.

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A new study from the University of Eastern Finland shows that a relatively high intake of dietary cholesterol, or eating one egg every day, is not associated with an elevated risk of dementia or Alzheimer’s disease. Furthermore, no association was found in persons carrying the APOE4 gene variant that affects cholesterol metabolism and increases the risk of memory disorders. APOE4 is common in Finland. The findings were published in the American Journal of Clinical Nutrition. Continue reading

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Frequent sauna bathing protects men against dementia

I don’t handle discomfort well, so sitting in a sauna sweating has never appealed to me. Having said that, as regular readers know I have lost three family members to Alzheimer’s or general dementia, so my radar shoots up to high when it comes to impaired cognition.

Frequent sauna bathing can reduce the risk of dementia, according to a recent study carried out at the University of Eastern Finland. In a 20-year follow-up, men taking a sauna 4-7 times a week were 66% less likely to be diagnosed with dementia than those taking a sauna once a week. The association between sauna bathing and dementia risk has not been previously investigated.

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The effects of sauna bathing on the risk of Alzheimer’s disease and other forms of dementia were studied in the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD), involving more than 2,000 middle-aged men living in the eastern part of Finland. Based on their sauna-bathing habits, the study participants were divided into three groups: those taking a sauna once a week, those taking a sauna 2-3 times a week, and those taking a sauna 4-7 times a week.

The more frequently saunas were taken, the lower was the risk of dementia. Among those taking a sauna 4-7 times a week, the risk of any form of dementia was 66% lower and the risk of Alzheimer’s disease 65% lower than among those taking a sauna just once a week. The findings were published recently in the Age and Ageing journal.

Previous results from the KIHD study have shown that frequent sauna bathing also significantly reduces the risk of sudden cardiac death, the risk of death due to coronary artery disease and other cardiac events, as well as overall mortality. According to Professor Jari Laukkanen, the study leader, sauna bathing may protect both the heart and memory to some extent via similar, still poorly known mechanisms. “However, it is known that cardiovascular health affects the brain as well. The sense of well-being and relaxation experienced during sauna bathing may also play a role.”

Tony

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The three stages of Alzheimer’s Disease – NIA

November is Alzheimer’s Awareness Month. As a person with family members on both sides who have suffered from dementia in general and Alzheimer’s in particular, I wanted to share this with you, from the Alzheimer’s Disease Education & Referral center.

The first symptoms of Alzheimer’s vary from person to person. For many, difficulty with tasks like word-finding, vision/spatial issues, and impaired reasoning or judgment, may signal the very early stages of Alzheimer’s disease.

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Typically, Alzheimer’s progresses in three stages: Continue reading

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What are some actions that prevent or delay Dementia and Alzheimer’s?

The question of brain games and other cerebral activities to prevent or delay dementia and Alzheimer’s Disease was taken up by The Ask the Expert column in the Alzheimer’s Prevention Registry.

“What kinds of brain activities did we find to be beneficial? While more research is needed to learn the best types of activities, the studies we reviewed included a wide range of possibilities….”

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“Here are some ideas:
•    Read a novel, a non-fiction book, a magazine, or newspaper.
•    Play board games with your children or grandkids.
•    Volunteer for a local organization.
•    Host a weekly card game for friends.
•    Register for an adult education class at your local college.
•    Look for art, cooking or other fun classes in your community.
•    Play video games with a young person in your life.
•    Attend a play or visit a museum.

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Can Ayurveda Help with Dementia and Alzheimer’s?

Because my family has suffered from both Alzheimer’s and dementia, I am especially sensitive to anything that might reduce my vulnerability to them. I really  liked the Tips to Nourish Your Brain at the end.

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Please be sure to check out my Page – Important facts about your brain (and exercise benefits) for more information.

Tony

STAYING HEALTHY WITH AYURVEDA

Alzheimer’s Disease is the most common cause of dementia, a brain disorder affecting the parts of the brain controlling thought, memory and language. About 4.5 million Americans suffer from Alzheimer’s and the number of cases are expected to quadruple by 2050. Ayurveda, the original health science of India, offers much needed knowledge on how to reverse aging trends, even in cases of brain deterioration such as Alzheimer’s disease.

Early detection provides a greater opportunity to delay or reverse the existing symptoms of aging disorders. Ayurveda, offers a comprehensive system of effective interventions.

A consultation with an Ayurvedic health expert using the ancient technique of Ayurvedic pulse assessment can help with early detection. Pulse assessment can help identify specific imbalances in the body which can predispose an individual to the onset of Alzheimer’s disease and other neurological disorders. This individual diagnosis is a powerful tool for designing an individualized treatment program and…

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