Tag Archives: aging

Women, exercise and longevity

Women who can exercise vigorously are at significantly lower risk of dying from heart disease, cancer and other causes. The research was presented 7 December at EuroEcho 2019, a scientific congress of the European Society of Cardiology (ESC).

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Study author Dr Jesús Peteiro, of University Hospital A Coruña, Spain advised women: “Exercise as much as you can. Fitness protects against death from any cause.”

Exercise is good for health and longevity, but information on women is scarce. Women generally live longer than men, so dedicated studies are needed. This study examined exercise capacity and heart function during exercise in women and their links with survival. The study included 4,714 adult women referred for treadmill exercise echocardiography because of known or suspected coronary artery disease. Continue reading

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CoQ10 and its dosage

I have to admit that I have been seeing items and ads about CoQ10 for years and never paid it much attention. I stumbled across this rundown in Medical News Today and was amazed at its functionality. I thought it would interest you.

CoQ10 is an antioxidant that exists in almost every cell of the human body. CoQ10 deficiency is associated with various medical conditions, such as heart disease, cancer, and Alzheimer’s disease.cells.jpg

 

Although the body naturally produces CoQ10, some people may benefit from taking supplements. Overall, CoQ10 supplements appear relatively safe and cause few side effects. Supplements are not regulated by the Food and Drug Administration (FDA) for purity or verified for labeling accuracy, so purchase only those products that have been tested by an independent lab.

People who are interested in trying CoQ10 supplements may want to consult a healthcare professional first. Experts do not recommend CoQ10 for people taking blood-thinning medications, insulin, or certain chemotherapy drugs. Continue reading

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Exercise and heart-healthy diet may slow memory problems developing

Cognitive impairment without dementia (CIND), or mild cognitive impairment, is a condition that affects your memory and may put you at risk for Alzheimer’s disease and dementia. According to the U.S. National Library for Medicine, signs of mild cognitive impairment may include frequently losing things, forgetting to go to events and appointments, and having more trouble coming up with words than other people of your age.

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My go-to exercise is biking. My dog comes along when the weather is willing. At 79, everything seems to be working …

Some experts believe that risk factors for heart disease also are risk factors for dementia and late-life cognitive decline and dementia. Recently, researchers examined two potential ways to slow the development of CIND based on what we know about preventing heart disease. They published the results of their study in the Journal of the American Geriatrics Society. Continue reading

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Improved fitness can mean living longer without dementia – Study

“It is important to say that it is never too late to begin exercising. The average participant in our study was around 60 years old at baseline, and improvement in cardio-respiratory fitness was strongly linked to lower dementia risk. Those who had poor fitness in the 1980s but improved it within the next decade could expect to live two years longer without dementia,” says Atefe Tari of the Cardiac Exercise Research Group (CERG) at the Norwegian University of Science and Technology (NTNU).

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Tari is lead author of a new study that was recently published in Lancet Public Health, a highly ranked journal in the prestigious Lancet family.

“Persistently low fitness is an independent risk factor for dementia and death due to dementia,” the authors concluded. Continue reading

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4 Tips for staying healthy this winter

Colder temperatures, inclement weather, reductions in the amount of daylight, and the spread of cold and flu viruses can all have a significant impact on your winter well-being, making it more challenging for you to stay safe and healthy.

Here are four important tips and tricks to help you cope with the cold weather, care for your immune system, and stay active until spring arrives, from Western Connecticut Medical Group.

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Tip 1: Prepare in Advance

A little prevention in the fall can help everyone — and especially older adults — avoid serious wintertime accidents. Precautions include preventing falls by installing handrails and fixing uneven or steep stairs before the weather turns cold and icy.

Fall is also a great time to work on increasing your flexibility. Increasing your flexibility decreases your risk of falling. And if you do fall, flexibility helps to decrease the severity of the injury. Stretching several times a week can improve your flexibility. Traditional stretching, yoga, tai chi, or Pilates are all great ways to stay flexible. Continue reading

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Number of people with dementia will double in twenty years

Regular readers are aware of my serious interest in dementia and Alzheimer’s Disease because I have lost several family members to a form of dementia. That is one of the reasons for my focus in this blog. There is no silver bullet to avoid Alzheimer’s yet, but exercise seems to work for keeping dementia at bay. Check out my Page – Important facts about your brain – (and exercise benefits) to learn more.

A new report projects the number of people living with dementia in the US will double to 13 million by 2040. The report estimates that the number of women diagnosed with dementia will rise to 8.5 million, and the number of men with dementia will reach 4.5 million. Source: Milken Institute

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Women caregivers are more likely to be impacted financially and leave their jobs or miss work to care for a family member. The image is in the public domain.

The number of Americans living with Alzheimer’s disease or other dementias will double to nearly 13 million over the next 20 years, according to the new Milken Institute report “Reducing the Cost and Risk of Dementia: Recommendations to Improve Brain Health and Decrease Disparities.”

Milken Institute research estimates that by 2020, roughly 4.7 million women in the US will have dementia, accounting for nearly two-thirds of all people living with the condition.

The number of both women and men living with dementia is projected to nearly double by 2040, with the number of women projected to rise to 8.5 million, and the number of men expected to reach 4.5 million (up from 2.6 million in 2020), according to the report, which was released at the 2019 Milken Institute Future of Health Summit in Washington, D.C.

Over the next 20 years, the economic burden of dementia will exceed $2 trillion, with women shouldering more than 80 percent of the cumulative costs.

“Longer lifespans are perhaps one of the greatest success stories of our modern public health system,” explains Nora Super, lead author of the report and senior director of the Milken Institute Center for the Future of Aging. “But along with this success comes one of our greatest challenges. Our risk of developing dementia doubles every five years after we turn 65; by age 85, nearly one in three of us will have the disease.”

“With no cure in sight, we must double down on efforts to reduce the cost and risk of dementia,” she added. “Emerging evidence shows that despite family history and personal genetics, lifestyle changes such as diet, exercise, and better sleep can improve health at all ages.”

In collaboration with partners such as UsAgainstAlzheimer’s, AARP and Bank of America, Super and her co-authors, Rajiv Ahuja and Kevin Proff, have developed detailed recommendations and goals for policymakers, businesses, and communities to improve brain health, reduce disparities, and ultimately change the trajectory of this devastating disease.

1) Promote strategies to maintain and improve brain health for all ages, genders, and across diverse populations
2) Increase access to cognitive testing and early diagnosis

3) Increase opportunities for diverse participation in research and prioritize funding to address health disparities

4) Build a dementia-capable workforce across the care continuum

5) Establish services and policies that promote supportive communities and workplaces for people with dementia and their caregivers

“As this important new report shows, dementia is one of the greatest public health challenges of our time,” said Sarah Lenz Lock, SVP, Policy & Brain Health at AARP. “It also demonstrates that we have the power to create change, whether by helping consumers maintain and improve their brain health, advancing research on the causes and treatment of dementia, or supporting caregivers who bear so much of the burden of this disease. We at AARP look forward to working with the Milken Institute and other key partners to achieve these goals.”

“Brain health broadens the fight against Alzheimer’s to include everyone and is the key to defeating stigma, increasing early detection, speeding up research — and ending this disease,” said Jill Lesser, a founding board member of UsAgainstAlzheimer’s. “This new look by the Milken Institute offers important recommendations and actions to help move us to an optimal system of brain health care in this country.”

Among the breakthrough findings, new data have “unveiled key discoveries about the differences between men’s and women’s brains, and how they age. Moreover, women typically take on greater caregiver responsibilities than men. Women caregivers are more likely to be impacted financially and leave their jobs or miss work to care for a family member. And research demonstrates that spousal caregivers may be at a higher risk of cognitive impairment or dementia than non-caregivers.”

“With this research, the Milken Institute has taken an important step to better understand the impacts of dementia on diverse populations,” said Lorna Sabbia, Head of Retirement and Personal Wealth Solutions, Bank of America. “This study, together with our own research on life stages, women, health and wellness, plays a critically important role in our efforts to educate and provide guidance to individuals and families throughout their financial lives.”

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Lifestyle changes can help maintain cognitive health – Rush

A recent two-year clinical trial in Finland (the FINGER Study) reported that a combination of physical activity, nutritional guidance, cognitive training, social activities and management of heart health risk factors protected cognition in healthy older adults who were identified as being at increased risk of cognitive decline. Currently no pharmacological treatments are available that rival this effect.

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“There is an urgent need to expand this work to test the generalizability, adaptability and sustainability of the FINGER study’s findings in geographically and culturally diverse populations in the U.S. and across the globe,” Morris said. “While there is no proven cure or prevention for dementia, current research shows that combining healthy lifestyle factors may counteract risk and help stave off dementia.” Continue reading

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Frailty: Rising global health burden for an aging society

Eat less; move more; live longer. Also, if you keep moving and using those muscles,  you will reduce your chances of suffering from frailty as you age.

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Despite the evidence on risk factors for frailty, and the substantial progress that has been made in frailty awareness, the biological mechanisms underlying its development are still far from understood and translation from research to clinical practice remains a challenge, according to a new series on Frailty just published by The Lancet. Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health and DeLamar Professor of Public Health Practice, and Professor of Epidemiology and Medicine, was part of an international group of experts who contributed to the series of papers which provide an up-to-date clinical overview on preventing, identifying and managing frailty as well as its global impact and burden. The series also offers evidence-based interventions for individuals with frailty. The findings are published online.

In the paper on Clinical Practice and Public Health, Fried, a renowned gerontologist and expert on aging, highlights two emerging lines of life course evidence on frailty. First, Fried and colleagues make the point that the risk of adverse outcomes can be predicted. Secondly, there is a clinical syndrome of frailty which is an outcome of biologic aging, although risk levels are substantially higher among those with certain diagnoses and comorbidities. She also notes that while great strides have been made in understanding frailty in the past two decades, many gaps in knowledge remain: no universal consensus exists on the definition of frailty or its assessment, and more robust, high-quality trials of strategies to prevent and manage frailty are needed.

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Exercise benefits your heart, despite your age …

Eat less; move more; live longer – no matter how old you are. Yes, the mantra of this blog applies to all of us, especially the old and out of shape …

A new study in the Canadian Journal of Cardiology showed that older individuals have the most to gain and may gain the most from rehabilitation programs, but this need is often ignored.

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Regular exercise is highly beneficial for all patients with cardiovascular disease regardless of age, report investigators in the Canadian Journal of Cardiology, published by Elsevier. Their results showed that the patients who benefited most from cardiac rehabilitation were those who started out with the greatest physical impairment. Continue reading

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Common nutrient supplementation may hold the answers to combating Alzheimer’s disease -Study

Everyone knows that there is no cure for Alzheimer’s Disease. One of the problems is that by the time  that symptoms become apparent, the disease has progressed so far as to be irreversible. This new study, however, appears to offer the chance of heading off the disease before it gets out of hand.

In a new study, Biodesign researchers reveal that a lifelong dietary regimen of choline holds the potential to prevent Alzheimer’s disease (AD).

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Choline is a safe and easy-to-administer nutrient that is naturally present in some foods and can be used as a dietary supplement. Lead author Ramon Velazquez and his colleagues at the ASU-Banner Neurodegenerative Disease Research Center (NDRC) looked into whether this nutrient could alleviate the effects of Alzheimer’s.

Earlier this year, Velazquez and colleagues found transgenerational benefits of AD-like symptoms in mice whose mothers were supplemented with choline. The latest work expands this line of research by exploring the effects of choline administered in adulthood rather than in fetal mice.

The study focuses on female mice bred to develop AD-like symptoms. Given the higher prevalence of AD in human females, the study sought to establish the findings in female mice. Results showed that when these mice are given high choline in their diet throughout life, they exhibit improvements in spatial memory, compared with those receiving a normal choline regimen.

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Harvard on resuming bike riding

I know that we are late in September and a lot of folks will be putting away their bikes ‘for the season.’ I ride year ’round here in Chicago and enjoy it. If you are one of those who haven’t ridden in a while and would like to take up a super form of exercise, I hope you will consider cycling. There are still a few good weeks left before the cold sets in. You can get started now.

The Harvard Health Publications has a nice positive blog post on starting cycling again presumably as a senior.

Heidi Godman, Executive Editor of the Harvard Health Letter, states that she loved riding as a kid, but now only rides occasionally.

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“It’s fun, it’s socially oriented, and it gets you outside and exercising,” says Dr. Clare Safran-Norton, a physical therapist at Harvard-affiliated Brigham and Women’s Hospital. Plus, cycling is an aerobic activity, it’s easy on the joints, and it helps build muscle and bone. Continue reading

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Writing into old age!

I have written repeatedly about how exercise benefits the brain as well as the body. Here is a wonderful post about exercising the ‘old noodle’ and how it has direct benefits on the brain.

Learning from Dogs

Thank goodness for this!

It’s not exactly a ball of fun growing old. But while somethings inevitable decline writing isn’t one of them. This is a fascinating article from The Conversation.

ooOOoo

One skill that doesn’t deteriorate with age

Reading and writing can prevent cognitive decline.
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Roger J. Kreuz, University of Memphis

When Toni Morrison died on Aug. 5, the world lost one of its most influential literary voices.

But Morrison wasn’t a literary wunderkind. “The Bluest Eye,” Morrison’s first novel, wasn’t published until she was 39. And her last, “God Help the Child,” appeared when she was 84. Morrison published four novels, four children’s books, many essays and other works of nonfiction after the age of 70.

Morrison isn’t unique in this regard. Numerous writers produce significant work well into their 70s, 80s and even their 90s. Herman Wouk, for example, was 97…

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Heart Attack Patients with Mild Cognitive Impairment Get Fewer Treatments

I guess this would be an example of the old adage, “When it rains, it pours.”

A new study finds people who have mild cognitive impairment (MCI), which lies on the continuum of cognitive decline between normal cognition and dementia, are less likely to receive proven heart attack treatment in the hospital.

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Researchers found no evidence that those with MCI would derive less benefit from evidence-based treatment that’s offered to their cognitively normal peers who have heart attacks, says lead author Deborah Levine, M.D., MPH.

“Patients should get the treatments they would want if they were properly informed,” says Levine, an associate professor of internal medicine and neurology at Michigan Medicine.

Some people with thinking, memory and language problems have MCI. Unlike dementia, which severely interferes with daily functioning and worsens over time, MCI does not severely interfere with daily functioning and might not worsen over time. Although people with MCI have an increased risk of developing dementia, it’s not an inevitable next step, Levine says.

“While some may progress to dementia, many will persist in having MCI, and a few will actually improve and revert to normal cognition,” says Levine, also a member of the University of Michigan Institute for Healthcare Policy and Innovation. “Many older adults with MCI live years with good quality of life, and so face common health risks of aging like heart attack and stroke.

“Clinicians, patients and families might be overestimating the risk of dementia after a mild cognitive impairment diagnosis even without realizing it. These older adults with MCI should still receive evidence-based treatments when indicated.” Continue reading

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Think declining mental sharpness ‘just comes with age’? Think again, say experts

Declining mental sharpness “just comes with age,” right? Not so fast, say geriatrics researchers and clinicians gathered at a prestigious 2018 conference hosted by the American Geriatrics Society (AGS) with support from the National Institute on Aging (NIA).

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In a report published in the Journal of the American Geriatrics Society (JAGS), attendees of a conference for the NIA’s Grants for Early Medical/Surgical Specialists Transition into Aging Research (GEMSSTAR) program describe how increasing evidence shows age-related diseases–rather than age itself–may be the key cause of cognitive decline. And while old age remains a primary risk factor for cognitive impairment, researchers believe future research–and sustained funding–could illuminate more complex, nuanced connections between cognitive health, overall health, and how we approach age. Continue reading

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Myths about high blood pressure – Rush

Blood pressure is like what Mark Twain said about the weather, “Everybody talks about it, but nobody does anything about it.” Well almost. I have found that blood pressure is one of those subjects that is widely and wildly misunderstood. I used to think it was like grey hair on old people. Everybody has it. I was dead wrong.

Few assumptions are more dangerous than this one: If you have high blood pressure, you know it.

Doctors refer to high blood pressure, or hypertension, as a silent killer because it rarely produces warning signs.

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“When symptoms do occur, such as headache, nosebleeds or blurry vision, high blood pressure may have already reached severe and possibly life-threatening levels,” says Daniel Pohlman, MD, a primary care doctor at Rush University Medical Center. Continue reading

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Aging arteries weaken memory – Study

Regular readers know of my concern about aging and its effect on cognition as three of my direct family members suffered from Alzheimer’s Disease and dementia. For that reason I try to keep my arteries flexible through my program of regular exercise. I know that there is no known way to prevent Alzheimer’s, but I am willing to take any physical measures that I can to reduce my chances. Check out my Page  – Important facts about your brain (and exercise benefits) for more details on this subject.

Researchers in Umeå, Sweden, have presented a model that explains why memory deteriorates as the body ages. With age, the brain receives an increased load from the heart’s beating as the body’s large arteries stiffen over the years, causing damage to the smallest blood vessels in the brain.

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The fact that human memory is deteriorating with increasing age is something that most people experience sooner or later, even among those who avoid diseases such as Alzheimer’s. Similarly, a connection between the ageing of the brain and the body is well known. However, the exact nature of this association is not known.

“We suggest a chain of events on how the aging of the brain and vessels are related,” says Lars Nyberg, professor at Umeå University.

What Umeå researchers Lars Nyberg and Anders Wåhlin have created is an explanatory model that starts with the heartbeat, and carries through the largest arteries in the body all the way to the finest vessels in the brain. An important feature of the model is that it provides a rationale why some cognitive processes may be particularly at risk for the proposed mechanism.

As the human body ages, large arteries, such as the aorta, stiffen and lose a large portion of their ability to absorb the pressure increase generated as the heart ejects blood into the arteries. Such pressure pulsatility is instead transmitted to smaller blood vessels, for example those in the brain. The smallest blood vessels in the brain, the capillaries, are subjected to an increased stress that causes damage to cells within and surrounding the capillary walls. These cells are important in the regulation of the capillary blood flow. If the smallest blood vessels are damaged, this is detrimental to the ability to increase the blood supply to the brain when coping with demanding cognitive processes.

According to the researchers’ model, the hippocampus in the brain is particularly vulnerable. The structure in that part of the brain is important for the episodic memory, that is, the ability to remember events from the past. The vulnerability of the hippocampus relates to the fact that it is located close to the large vessels and thus is exposed to the increased load early in the chain. In a young and healthy person, the pulsations are soft, but in an ageing person the pulsations can be so powerful that they affect the brain tissue and can damage the blood supply to memory processes.

The Umeå researchers’ model is based on a number of previous studies from the last five years.

“We have laid the puzzle of current and verified research in different fields to a broader and more detailed picture of the course of events. It will form a starting point for future research to gain a better understanding and, in the long term, researchers may also find solutions to slow down the process,” says Anders Wåhlin.

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