New research reveals how key proteins interact to regulate the body’s response to stress
Targeting these proteins may help treat or prevent stress-related psychiatric disorders
The biological mechanisms behind stress-related psychiatric conditions, including major depressive disorder and post-traumatic stress disorder (PTSD), are poorly understood.
New research now details the interplay between proteins involved in controlling the body’s stress response and points to potential therapeutic targets when this response goes awry. The study, which was conducted by an international team led by investigators at McLean Hospital, appears in the journal Cell Reports.
The COVID-19 pandemic could inflict long-lasting emotional trauma on an unprecedented global scale, leaving millions grappling with debilitating psychological disorders, according to a new study commissioned by an interdisciplinary team of researchers from Case Western Reserve University.
“There are some valid concerns that this coronavirus pandemic could cause emotional trauma and PTSD at a level we’ve never seen before,” said Megan Holmes, an associate professor of social work and the founding director of the Center on Trauma and Adversity at the university’s Jack, Joseph and Morton Mandel School of Applied Social Sciences. Continue reading →