Am I the only person who thinks these AXIRON commercials are more than a little frightening? In case you haven’t seen one, AXIRON is one of the ‘low T’ drugs, the euphemism for low testosterone. To judge by the number of these ads I see on TV, the majority of men in this country seem to suffer from it. But, low testosterone is not the issue here. It’s this power house of a drug to address it.
These AXIRON commercials recite a litany of warnings to the user, his wife/girlfriend and also any children within reach. How strong is this stuff?
Before I go further here is one of the commercials and you can try to keep up with the warnings for yourself.
Short of taking shorthand, I doubt you were able to get them all. But, if you weren’t able to keep up, here is the 411 direct from the AXIRON page.
“Important Safety Information for AXIRON (testosterone) topical solution
What is the most important information I should know about AXIRON?
AXIRON can transfer from your body to others. This can happen if other people come into contact with the area where the AXIRON was applied. Signs of puberty that are not expected (for example, pubic hair) have happened in young children who were accidentally exposed to testosterone through skin to skin contact with men using topical testosterone products like AXIRON. Women and children should avoid contact with the unwashed or unclothed area where AXIRON has been applied. If a woman or child makes contact with the application area, the contact area on the woman or child should be washed well with soap and water right away.
To lower the risk of transfer of AXIRON from your body to others, follow these important instructions:
Apply AXIRON only to your armpits.
Wash your hands right away with soap and water after applying AXIRON.
After the solution has dried, cover the application area with clothing. Keep area covered until you have washed the application area well or have showered.
If you expect another person to have direct skin-to-skin contact with your armpits, first wash the application area well with soap and water.
Stop using AXIRON and call your healthcare provider right away if you see any signs and symptoms in a child or a woman that may have occurred through accidental exposure to AXIRON. Signs and symptoms in children may include enlarged penis or clitoris; early development of pubic hair; increased erections or sex drive; aggressive behavior. Signs and symptoms in women may include changes in body hair and a large increase in acne.
Who should not use AXIRON?
Do not use AXIRON if you:
have or might have prostate cancer
have breast cancer
are pregnant or may become pregnant or are breast-feeding. AXIRON may harm your unborn or breast-feeding baby.
Women who are pregnant or who may become pregnant should avoid contact with the area of skin where AXIRON has been applied.
What should I tell my healthcare provider before using AXIRON?
Before you use AXIRON, tell your healthcare provider if you have:
or might have prostate cancer
urinary problems due to an enlarged prostate
kidney or liver problems
problems breathing while you sleep (sleep apnea)
any other medical conditions
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Using AXIRON with other medicines can affect each other. Especially, tell your healthcare provider if you take:
medicines that decrease blood clotting
What are the possible side effects of AXIRON?
AXIRON can cause serious side effects. Call your healthcare provider right away if you have any of the following:
If you already have enlargement of your prostate gland, your signs and symptoms can get worse while using AXIRON. This can include: increased urination at night, trouble starting your urine stream, having to pass urine many times during the day, having an urge that you have to go to the bathroom right away, having a urine accident, being unable to pass urine or weak urine flow.
Possible increased risk of prostate cancer. Your healthcare provider should check for prostate cancer or any other prostate problems before you start and while you use AXIRON.
In large doses AXIRON may lower your sperm count.
Swelling of your ankles, feet, or body.
Enlarged or painful breasts.
Problems breathing while you sleep (sleep apnea).
Blood clots in the legs. This can include pain, swelling or redness of your legs.
The most common adverse events include: skin redness or irritation where AXIRON is applied, increased red blood cell count, headache, diarrhea, vomiting, and increase in blood level of Prostate Specific Antigen (a test used to screen for prostate cancer). Other side effects include more erections than are normal for you or erections that last a long time.
AXIRON is flammable until dry. Let AXIRON dry before smoking or going near an open flame.
Axiron is available by prescription only
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call
For more information, please see full Prescribing Information, including Boxed Warning regarding the risk of transfer to others, and Medication Guide.
There did you get all that? As macabre as these warning are, I must confess the most bizarre was the warning that AXIRON is FLAMMABLE(!) Don’t smoke or go near open flame!!?? My God! People pay for this stuff?
As a lifetime game player and long time gambler, speculator and investor, I always try to balance risk and reward before entering into a situation with risk. I think the AXIRON situation is the more incredibly scewed risk/reward ratio I have ever seen.
I wouldn’t touch this stuff with a ten foot pole, but if you haven’t been put off by the warnings, check it out.
I invite any readers who may be AXIRON users to share their experience with the blog.