A recent trial found that getting moving can improve liver health in people with obesity, even without weight loss, according to Tufts Health & Nutrition Letter.
Non-alcoholic fatty liver disease (NAFLD) is a common condition in which excess fat accumulates in the liver, often in response to diets high in starch and sugar. NAFLD is the most common form of liver disease in the U.S. and may be present in more than 90 percent of individuals with obesity and 75 percent with overweight. According to the National Institutes of Health, people with NAFLD are at high risk of developing liver inflammation that can lead to cirrhosis (advanced scarring) and liver failure.
In this trial, 83 Japanese men with obesity participated for three months in either an aerobic exercise program (fast walking or light jogging for 90 minutes three days a week) or calorie restriction with the help of a registered dietitian. In the activity group, muscle strength increased, markers of general inflammation and oxidative stress decreased, and liver health improved, even without weight loss.
This study adds to a large body of science that physical activity, like a healthy diet, has many benefits beyond weight loss.”
The liver has a unique ability to regenerate after damage. However, it was unknown whether this ability decreases as we age. International scientists led by Dr. Olaf Bergmann at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden used a technique known as retrospective radiocarbon birth dating to determine the age of the human liver. They showed that no matter the person’s age, the liver is always on average less than three years old. The results demonstrate that aging does not influence liver renewal, making the liver an organ that replaces its cells equally well in young and old people.
The liver is an essential organ that takes care of clearing toxins in our bodies. Because it constantly deals with toxic substances, it is likely to be regularly injured. To overcome this, the liver has a unique capacity among organs to regenerate itself after damage. Because a lot of the body’s ability to heal itself and regenerate decreases as we age, scientists were wondering if the liver’s capacity to renew also diminishes with age.
The nature of liver renewal in humans also remained a mystery. The animal models provided contradictory answers. “Some studies pointed to the possibility that liver cells are long-lived while others showed a constant turnover. It was clear to us that if we want to know what happens in humans, we need to find a way to directly assess the age of human liver cells,” says Dr. Olaf Bergmann, research group leader at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden.
It is estimated that about one in four adults worldwide has an abnormal build-up of fat in the liver, called non-alcoholic fatty liver disease (NAFLD).
NAFLD can lead to permanent liver damage, and heart disease is the leading cause of death in people with fatty liver disease.
Because NAFLD is often missed in routine medical screening, the new American Heart Association scientific statement raises awareness and understanding about its link to heart disease and to outline how to prevent and diagnose the condition.
It is estimated that about one in four adults worldwide has a liver condition that is a risk factor for heart disease, according to a new American Heart Association scientific statement published today in the Association’s peer-reviewed journal Arteriosclerosis, Thrombosis, and Vascular Biology. The condition, called nonalcoholic fatty liver disease (NAFLD), occurs when abnormally elevated amounts of fat are deposited in the liver, sometimes resulting in inflammation and scarring. The prevalence of NAFLD is an estimate, given the challenges in diagnosing the condition, which are detailed in the statement.
An American Heart Association scientific statement is an expert analysis of current research and may inform future guidelines. Professional organizations specializing in gastroenterology have previously published statements on the condition, however, they focus on liver toxicity (including scarring, cirrhosis and liver cancer) rather than heart disease risk. This is the Association’s first statement about NAFLD.
“Nonalcoholic fatty liver disease (NAFLD) is a common condition that is often hidden or missed in routine medical care. It is important to know about the condition and treat it early because it is a risk factor for chronic liver damage and cardiovascular disease,” said P. Barton Duell, M.D., FAHA, chair of the statement writing committee and professor of medicine in the Knight Cardiovascular Institute and Division of Endocrinology, Diabetes and Clinical Nutrition at Oregon Health & Science University in Portland, Oregon.
There are two types of NAFLD: one when only fat is present in the liver (called non-alcoholic fatty liver), and the other when inflammation and scarring are also present (called non-alcoholic steatohepatitis, or NASH). Excess alcohol intake can cause similar fat deposits and liver dysfunction, so the term NAFLD is used to differentiate between disease caused by excess alcohol intake vs. disease without alcohol as the underlying cause.
I get blood work done at least once a year and confess that I do not know what all the information they get means. Thought this piece from Medical News Today might be useful in that regard.
Doctors regularly order blood tests to get an idea of the overall health of their patients.
One of the things they check for is MCH levels.
These levels are regularly used to help diagnose blood disorders but can be difficult to understand. Different MCH levels may cause a variety of symptoms, which will require individual treatments.
What is MCH?
MCH stands for mean corpuscular hemoglobin.
MCH levels refer to the average amount of hemoglobin found in the red blood cells in the body. Hemoglobin is a protein in the blood that allows red blood cells to deliver oxygen to the cells and tissues in the body.
What is a CBC test?
A complete blood count test, or simply CBC test, is designed to give doctors a general overview of a person’s health. The test can help screen people for a variety of issues at once and may help diagnose conditions, such as bleeding disorders, infections, and anemia. Continue reading →
It sets in the middle of our stomach and regulates some of the most important functions of our body. It performs more than 500 different chemical functions. And most of us don’t know the first thing about it.