A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis — the process of cell death that is usually caused by infections and results in excess inflammation in the body — and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.
The discovery, which is reported in Nature Communications, means that scientists have a new way to study diseases that are related to malfunctioning cell death processes, like some cancers, and infections that can be complicated by out-of-control inflammation caused by the process. These infections include sepsis, for example, and acute respiratory distress syndrome, which is among the major complications of COVID-19 illness.
Here’s a sweet story from Newcastle University. Layering minute amounts of Manuka honey between layers of surgical mesh acts as a natural antibiotic that could prevent infection following an operation, new research has shown.
Meshes are used to help promote soft tissue healing inside the body following surgery and are common in operations such as hernia repair. However, they carry with them an increased risk of infection as the bacteria are able to get a hold inside the body by forming a biofilm on the surface of the mesh.
Skin and soft tissue infections are the most common bacterial infections, accounting for around 10% of hospital admissions, and a significant proportion of these are secondary infections following surgery. Continue reading →