Getting a consistent good night’s sleep supports normal production and programming of hematopoietic stem cells, a building block of the body’s innate immune system, according to a small National Institutes of Health-supported study in humans and mice. Sleep has long been linked to immune function, but researchers discovered that getting enough of it influenced the environment where monocytes – a type of white blood cell – form, develop, and get primed to support immune function. This process, hematopoiesis, occurs in the bone marrow.

The study published in the Journal of Experimental Medicine(link is external).
“What we are learning is that sleep modulates the production of cells that are the protagonists – the main actors – of inflammation,” said Filip K. Swirski, Ph.D., a senior study author and director of the Cardiovascular Research Institute at Icahn School of Medicine at Mount Sinai, New York City. “Good, quality sleep reduces that inflammatory burden.”