A study conducted at the University of Helsinki and the Helsinki University Hospital suggests that the APOE4 allele may also increase cerebral microhaemorrhages related to COVID-19 and associate with mental fatigue related to long COVID.
Roughly one-third of Finns carry the APOE4 allele, a genetic variant that predisposes carriers to Alzheimer’s disease. Globally, researchers have reported observations that show a link between APOE4 and COVID-19, both in terms of increased susceptibility to SARS-CoV-2 infection and COVID-19 mortality. Now, a research group at the University of Helsinki and the Helsinki University Hospital (HUS) has investigated the link between the APOE4 allele and the severity of COVID-19 in the Finnish population.
Breathe in, breathe out. That’s how easy it is for SARS-CoV-2, the virus that causes COVID-19, to enter your nose. And though remarkable progress has been made in developing intramuscular vaccines against SARS-CoV- 2, such as the readily available Pfizer, Moderna and Johnson & Johnson vaccines, nothing yet – like a nasal vaccine – has been approved to provide mucosal immunity in the nose, the first barrier against the virus before it travels down to the lungs.
But now, we’re one step closer.
Navin Varadarajan, University of Houston M.D. Anderson Professor of Chemical and Biomolecular Engineering, and his colleagues, are reporting in iScience the development of an intranasal subunit vaccine that provides durable local immunity against inhaled pathogens.
Considering the greater good by social distancing during a pandemic turns out to have an attractive personal benefit: A new study has found that staying away from others also reduces an individual person’s chances of contracting COVID-19. Social distancing is not just for the benefit of others.
Researchers presented study participants with virtual behavior scenarios of various public settings – a grocery store, a crowded beach, a crosswalk – and asked them to place themselves or fictional people in those contexts based on their social distancing preferences.
A comprehensive study of immune responses to SARS-CoV-2 associates mild disease with comparatively high levels of antibodies that target the viral spike protein. But all antibodies wane within months.
COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine.
The findings identify new links between the course of the disease and a patient’s immune response. They also raise concerns about whether people can be re-infected, whether antibody tests to detect prior infection may underestimate the breadth of the pandemic and whether vaccinations may need to be repeated at regular intervals to maintain a protective immune response.
It’s fair to say that the novel coronavirus pandemic has changed the way people shop—and also the items they shop for. There has been a shortage of things one might expect: toilet paper, disinfectant wipes, and thermometers. But, there are other—more surprising—items like yoga mats, yeast, and, more recently, pulse oximeters.
So, what, exactly, is a pulse oximeter?
It’s an electronic device that clips onto a patient’s finger to measure heart rate and oxygen saturation in his or her red blood cells—the device is useful in assessing patients with lung disease. Pulse oximeters started to fly off store (and online) shelves when people learned that low oxygen saturation levels can be a sign of COVID-19, according to Yale Medicine.
The pulse oximeter pictured here is a neat little gadget that Costco is selling. As you can see from the picture, it monitors your Heart Rate (pulse), Oxygen Level and your Blood Flow. In sum, very useful information provided in a matter of seconds with no penetration of your flesh. There is even a cool graph of your heart beat on the screen. In this period of wearables, the Pulse Oximeter is reminiscent of the first cell phones. But, you can feel like a camp counselor and wear it around your neck using the attached lanyard.
Before I go into explanations and specifications, I want to disclose that I bought one of these and have been using it for a week now. Love it! It is particularly useful when I am stair climbing. I like to get a handle on how my heart rate accelerates on…
As communities across the U.S. have struggled to cope with the effects of the COVID-19 pandemic, many have focused on the lack of widespread testing as a major barrier to safely reopening the country. As progress has been made on this front, concern has shifted to testing accuracy, predominantly with antibody tests, which are designed to identify prior infection.
But according to a new Dartmouth-led paper published in the New England Journal of Medicine, more emphasis should be placed on addressing the inaccuracy of diagnostic tests, which play a key role in containing the pandemic.