Tag Archives: covid-19 effects

Pregnant women with COVID-19 face high mortality rate

In a worldwide study of 2,100 pregnant women, those who contracted COVID-19 during pregnancy were 20 times more likely to die than those who did not contract the virus, according to the University of Washington (UW).

UW Medicine and University of Oxford doctors led this first-of-its-kind study, published today in JAMA Pediatrics. The investigation involved more than 100 researchers and pregnant women from 43 maternity hospitals in 18 low-, middle- and high-income nations; 220 of the women received care in the United States, 40 at UW Medicine. The research was conducted between April and August of 2020.  

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The study is unique because each woman affected by COVID-19 was compared with two uninfected pregnant women who gave birth during the same span in the same hospital.

Aside from an increased risk of death, women and their newborns were also more likely to experience preterm birth, preeclampsia and admission to the ICU and/or intubation. Of the mothers who tested positive for the disease, 11.5% of their babies also tested positive, the study found. 

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Past COVID-19 infection doesn’t fully protect young people against re-infection – Study

Although antibodies induced by SARS-CoV-2 infection are largely protective, they do not completely protect against reinfection in young people, as evidenced through a longitudinal, prospective study of more than 3,000 young, healthy members of the US Marines Corps conducted by researchers at the Icahn School of Medicine at Mount Sinai and the Naval Medical Research Center, published April 15 in The Lancet Respiratory Medicine.

“Our findings indicate that reinfection by SARS-CoV-2 in health young adults is common” says Stuart Sealfon, MD, the Sara B. and Seth M. Glickenhaus Professor of Neurology at the Icahn School of Medicine at Mount Sinai and senior author of the paper. “Despite a prior COVID-19 infection, young people can catch the virus again and may still transmit it to others. This is an important point to know and remember as vaccine rollouts continue. Young people should get the vaccine whenever possible, since vaccination is necessary to boost immune responses, prevent reinfection, and reduce transmission.”

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The study, conducted between May and November 2020, revealed that around 10 percent (19 out of 189) of participants who were previously infected with SARS-CoV-s (seropositive) became reinfected, compared with new infections in 50 percent (1.079 out of 2,247) of participants who had not been previously infected (seronegative). While seronegative study participants had a five times greater risk of infection than seropositive participants, the study showed that seropositive people are still at risk of reinfection.

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Stroke risk higher than expected among COVID-19 patients

New research found patients hospitalized with COVID-19 had a higher risk of stroke, compared with patients who had similar infectious conditions such as influenza and sepsis in prior studies. Those who had an ischemic stroke were more likely to be older, male, Black race, or have high blood pressure, Type 2 diabetes or an irregular heartbeat (atrial fibrillation) compared with other COVID-19 patients, according to late-breaking science presented today at the American Stroke Association’s International Stroke Conference 2021. The meeting was held virtually, March 17-19, 2021 and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health.

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For this analysis, researchers accessed the American Heart Association’s COVID-19 Cardiovascular Disease Registry to investigate stroke risk among patients hospitalized for COVID-19, their demographic characteristics, medical histories and in-hospital survival. The COVID-19 Registry data pulled for this study included more than 20,000 patients hospitalized with COVID-19 across the U.S. between January and November 2020.

“These findings suggest that COVID-19 may increase the risk for stroke, though the exact mechanism for this is still unknown,” said lead study author Saate S. Shakil, M.D., a cardiology fellow at the University of Washington in Seattle. “As the pandemic continues, we are finding that coronavirus is not just a respiratory illness, but a vascular disease that can affect many organ systems.”

Two hundred eighty-one people (1.4%) in the COVID-19 CVD Registry had a stroke confirmed by diagnostic imaging during hospitalization. Of these, 148 patients (52.7%) experienced ischemic stroke; 7 patients (2.5%) had transient ischemic attack (TIA); and 127 patients (45.2%) experienced a bleeding stroke or unspecified type of stroke.

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LED lights found to kill coronavirus: Global first in fight against COVID-19 – TAU

Researchers from Tel Aviv University (TAU) have proven that the coronavirus can be killed efficiently, quickly, and cheaply using ultraviolet (UV) light-emitting diodes (UV-LEDs). They believe that the UV-LED technology will soon be available for private and commercial use.

This is the first study conducted on the disinfection efficiency of UV-LED irradiation at different wavelengths or frequencies on a virus from the family of coronaviruses. The study was led by Professor Hadas Mamane, Head of the Environmental Engineering Program at TAU’s School of Mechnical Engineering, Iby and Aladar Fleischman Faculty of Engineering. The article was published in November 2020 issue of the Journal of Photochemistry and Photobiology B: Biology.

“The entire world is currently looking for effective solutions to disinfect the coronavirus,” said Professor Mamane. “The problem is that in order to disinfect a bus, train, sports hall, or plane by chemical spraying, you need physical manpower, and in order for the spraying to be effective, you have to give the chemical time to act on the surface. Disinfection systems based on LED bulbs, however, can be installed in the ventilation system and air conditioner, for example, and sterilize the air sucked in and then emitted into the room.

“We discovered that it is quite simple to kill the coronavirus using LED bulbs that radiate ultraviolet light,” she explained. “We killed the viruses using cheaper and more readily available LED bulbs, which consume little energy and do not contain mercury like regular bulbs. Our research has commercial and societal implications, given the possibility of using such LED bulbs in all areas of our lives, safely and quickly.”

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Research strongly suggests COVID-19 virus enters the brain

More and more evidence is coming out that people with COVID-19 are suffering from cognitive effects, such as brain fog and fatigue.

And researchers are discovering why. The SARS-CoV-2 virus, like many viruses before it, is bad news for the brain. In a study published Dec.16 in Nature Neuroscience, researchers found that the spike protein, often depicted as the red arms of the virus, can cross the blood-brain barrier in mice.

The S1 protein likely causes the brain to release inflammatory products causing a storm in the brain, researchers said. Credit Alice Gray

This strongly suggests that SARS-CoV-2, the cause of COVID-19, can enter the brain.

The spike protein, often called the S1 protein, dictates which cells the virus can enter. Usually, the virus does the same thing as its binding protein, said lead author William A. Banks, a professor of medicine at the University of Washington School of Medicine and a Puget Sound Veterans Affairs Healthcare System physician and researcher. Banks said binding proteins like S1 usually by themselves cause damage as they detach from the virus and cause inflammation.

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Pandemic has severely disrupted sleep, increasing stress and medication use – Study

The COVID-19 pandemic is seriously affecting the sleep habits of half of those surveyed in a new study from The Royal and the University of Ottawa, leading to further stress and anxiety plus further dependence on sleep medication.

The global pandemic’s impact on daily routines extends to the bed, according to ‘Profiles of sleep changes during the COVID?19 pandemic: Demographic, behavioural and psychological factors’. The study was led by Principal Investigator Rébecca Robillard, an Assistant Professor and co-director of the Sleep Laboratory of the School of Psychology at the University of Ottawa, and Head Scientist in the Sleep Research Unit at The Royal Institute of Mental Health Research and published in the Journal of Sleep Research.

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Dr. Robillard and her team, which was comprised of nearly two dozen scientists from across North America, conducted an online survey of 5,525 Canadian during the early phase of the COVID-19 pandemic. She walked us through some of the study’s most important findings.

How has the pandemic affected our sleep?

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Pandemic’s effect on mental health swift and harsh on vulnerable families

As cases and hospitalizations from the pandemic begin to decline, collateral damage on the populace appears to be on the rise.

In just a few months, the COVID-19 pandemic swiftly and substantially worsened mental health among U.S. hourly service workers and their children – especially those experiencing multiple hardships, according to new research from the Center for Child and Family Policy at Duke University and Barnard College.

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The study leverages real-time, daily survey data collected from Feb. 20, before the pandemic hit the U.S., to April 27, when it was well underway, to examine how the crisis affected parents’ and children’s mental well-being. The 645 survey respondents were parents of young children working in hourly service-industry positions in retail, food service or hotel industries in a large U.S. city.

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COVID-19 can damage heart, even after recovery – AHA

A growing number of studies suggest many COVID-19 survivors experience some type of heart damage, even if they didn’t have underlying heart disease and weren’t sick enough to be hospitalized. This latest twist has health care experts worried about a potential increase in heart failure, according to a report in the American Heart Association News.

“Very early into the pandemic, it was clear that many patients who were hospitalized were showing evidence of cardiac injury,” said Dr. Gregg Fonarow, chief of the division of cardiology at the University of California, Los Angeles. “More recently, there is recognition that even some of those COVID-19 patients not hospitalized are experiencing cardiac injury. This raises concerns that there may be individuals who get through the initial infection, but are left with cardiovascular damage and complications.”

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Our ability to focus may falter after eating one meal high in saturated fat

Fatty food may feel like a friend during these troubled times, but new research suggests that eating just one meal high in saturated fat can hinder our ability to concentrate — not great news for people whose diets have gone south while they’re working at home during the COVID-19 pandemic.

The study compared how 51 women performed on a test of their attention after they ate either a meal high in saturated fat or the same meal made with sunflower oil, which is high in unsaturated fat.

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Study in Chinese Doctors Shows Mental Toll of COVID-19 Caring

They worked in hospitals hundreds of miles from the epicenter of COVID-19. Their city of 24 million people locked down hard enough, and did enough testing, that it only had a few hundred cases of the disease.

But hundreds of young Chinese doctors in a new study still experienced a sharp drop in mood, a  rise in depression and anxiety symptoms, and a doubling of their fear of workplace violence, in just the first month of the coronavirus pandemic.

The new findings, published in JAMA Network Open by an American and Chinese team, show in stark terms the potential mental toll of being a frontline healthcare worker in the time of COVID-19.

The rise in symptoms among 385 first year medical residents in Shanghai contrasts with data from members of the previous year’s crop of residents who took part in the same study from 2018 to 2019.

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Chapman University national study highlights wide-ranging effects of COVID-19 pandemic

Everyone experiences events in their own unique way. Take the COVID-19 pandemic – please. (With apologies to Henny Youngman). Turns out there is a negative bias to most peoples’ perceptions.

The survey examined the experiences of 4,149 adults living in the United States and how the crisis is impacting their mental health, physical health, romantic relationships, encounters of prejudice.

The Chapman University National COVID-19 and Mental Health Survey provides an in-depth look at the experiences of 4,149 adults living in the United States. The study asked questions about how the COVID-19 pandemic is impacting people’s mental health, physical health, romantic relationships and encounters of prejudice and discrimination.

What Are the Effects of COVID-19 on Mental Health and Behaviors?

Conducted at the end of April 2020, survey findings revealed that most people are staying home more than normal (89%), and the majority reported feeling more stressed (61%), nervous, anxious, or on edge (60%), and feeling down, depressed, or hopeless (45%) than normal due to the effects of the COVID-19 pandemic. People attributed the changes in their health behaviors to the pandemic, with about one-third reporting eating more because of stress (37%), eating more junk food (41%) and getting less exercise (35%).

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