Tag Archives: Cognitive Function

Orienteering can train the brain, may help fight cognitive decline

The sport of orienteering, which draws on athleticism, navigational skills and memory, could be useful as an intervention or preventive measure to fight cognitive decline related to dementia, according to new research from McMaster University.

Researchers hypothesized that the physical and cognitive demands of orienteering, which integrates exercise with navigation, may stimulate parts of the brain that our ancient ancestors used for hunting and gathering. The brain evolved thousands of years ago to adapt to the harsh environment by creating new neural pathways. 

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Those same brain functions are not as necessary for survival today due to modern conveniences such as GPS apps and readily available food. Researchers suggest it is a case of “use it or lose it.”

“Modern life may lack the specific cognitive and physical challenges the brain needs to thrive,” says Jennifer Heisz, Canada Research Chair in Brain Health and Aging at McMaster University, who supervised the research. “In the absence of active navigation, we risk losing that neural architecture.”

Heisz points to Alzheimer’s disease, in which losing the ability to find one’s way is among the earliest symptoms, affecting half of all afflicted individuals, even in the mildest stage of the disease.

In the study, published in the journal PLoS ONE, researchers surveyed healthy adults, ranging in age from 18 to 87 with varying degrees of orienteering expertise (none, intermediate, advanced and elite).

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Machine learning gives nuanced view of Alzheimer’s stages

 A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer’s disease in people who are either cognitively normal or experiencing mild cognitive impairment.

The modeling showed that predicting the future decline into dementia for individuals with mild cognitive impairment is easier and more accurate than it is for cognitively normal, or asymptomatic, individuals. At the same time, the researchers found that the predictions for cognitively normal subjects is less accurate for longer time horizons, but for individuals with mild cognitive impairment, the opposite is true.

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The modeling also demonstrated that magnetic resonance imaging (MRI) is a useful prognostic tool for people in both stages, whereas tools that track molecular biomarkers, such as positron emission tomography (PET) scans, are more useful for people experiencing mild cognitive impairment.

The team’s paper, “Machine Learning Based Multi-Modal Prediction of Future Decline Toward Alzheimer’s Disease: An Empirical Study,” published Nov. 16 in PLOS ONE. The lead author is Batuhan Karaman, a doctoral student in the field of electrical and computer engineering.

Alzheimer’s disease can take years, sometimes decades, to progress before a person exhibits symptoms. Once diagnosed, some individuals decline rapidly but others can live with mild symptoms for years, which makes forecasting the rate of the disease’s advancement a challenge.

“When we can confidently say someone has dementia, it is too late. A lot of damage has already happened to the brain, and it’s irreversible damage,” said senior author Mert Sabuncu, associate professor of electrical and computer engineering in the College of Engineering and of electrical engineering in radiology at Weill Cornell Medicine.

“We really need to be able to catch Alzheimer’s disease early on,” Sabuncu said, “and be able to tell who’s going to progress fast and who’s going to progress slower, so that we can stratify the different risk groups and be able to deploy whatever treatment options we have.”

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Omega-3s linked to improved midlife brain structure, cognition

Holy mackerel! Could eating salmon, cod, tuna, herring or sardines keep our brains healthy and our thinking agile in middle age? New research makes this connection.

Eating cold-water fish and other sources of omega-3 fatty acids may preserve brain health and enhance cognition in middle age, new evidence indicates.

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Having at least some omega-3s in red blood cells was associated with better brain structure and cognitive function among healthy study volunteers in their 40s and 50s, according to research published online Oct. 5 in Neurology®, the medical journal of the American Academy of Neurology. Faculty of The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and other investigators of the Framingham Heart Study conducted the analysis.

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What to know about cardiovascular disease symptoms – AHA

Symptoms of cardiovascular problems run the gamut. Some – like chest pain during a heart attack or a droopy face during a stroke – are sudden and severe, while others last years with varying intensity. Factors such as sex, cognitive function and depression can complicate the recognition or diagnosis of symptoms, according to the American Heart Association.

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In a new report, experts detail the latest knowledge on cardiovascular disease symptoms with the goal to improve patient care and identify where more research is needed.

“Symptoms are a big part of how we assess a patient when they come to see us in clinic and how we make decisions about what the best treatment is for an individual,” said Megan Streur, a nurse practitioner at the Heart Institute at UW Medical Center in Seattle. “But at the same time, there’s a lot that we still don’t understand about the variability of symptoms in the same condition across different individuals.”

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Why is music good for the brain? – Harvard

Can music really affect your well-being, learning, cognitive function, quality of life, and even happiness, asks Harvard Health Publishing in a recent blog post. I have to confess that as a daily bike rider who plays music on a blue tooth speaker while riding, I was very happy to learn this.

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A recent survey on music and brain health conducted by AARP revealed some interesting findings about the impact of music on cognitive and emotional well-being:

  • Music listeners had higher scores for mental well-being and slightly reduced levels of anxiety and depression compared to people overall.
  • Of survey respondents who currently go to musical performances, 69% rated their brain health as “excellent” or “very good,” compared to 58% for those who went in the past and 52% for those who never attended.
  • Of those who reported often being exposed to music as a child, 68% rated their ability to learn new things as “excellent” or “very good,” compared to 50% of those who were not exposed to music.
  • Active musical engagement, including those over age 50, was associated with higher rates of happiness and good cognitive function.
  • Adults with no early music exposure but who currently engage in some music appreciation show above average mental well-being scores.

Let’s take a closer look at this study

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Key Mental Abilities Can Actually Improve During Aging

It’s long been believed that advancing age leads to broad declines in our mental abilities. Now, new research from Georgetown University Medical Center offers surprisingly good news by countering this view.

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The findings, published August 19, 2021, in Nature Human Behavior, show that two key brain functions, which allow us to attend to new information and to focus on what’s important in a given situation, can in fact improve in older individuals. These functions underlie critical aspects of cognition such as memory, decision making, and self-control, and even navigation, math, language and reading.

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Cognitive behavior therapy tops other psychotherapies in reducing inflammation

A review of 56 randomized clinical trials finds that psychological and behavioral therapies may be effective non-drug treatments for reducing disease-causing inflammation in the body.

The results of the analysis, published in JAMA Psychiatry, found that cognitive behavior therapy, or CBT, was superior to other psychotherapies at boosting the immune system.

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How Good is Vitamin D For You? – Infographic

Vitamin D is the new rock star of the vitamin world. To read further on its benefits check out: Vitamin D and Cognitive Function, Vitamin D Deficiency May be Linked to Heart Disease, Vitamin D Deficiency May Compromise Immune Function, Calcium and Vitamin D Help Hormones Help Bones, Vitamin D Improves Mood and Blood Pressure in Women with Diabetes, Vitamin D and Your Body – Harvard, What are the ABC’s of Vitamins?

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