Whether you are pear-shaped or apple shaped depends a lot on your genes it seems.
A recent study from Uppsala University has found that whether you store your fat around the trunk or in other parts of your body is highly influenced by genetic factors and that this effect is present predominantly in women and to a much lower extent in men. In the study, which is published in Nature Communications, the researchers measured how fat was distributed in nearly 360,000 voluntary participants.
“We know that women and men tend to store fat differently — women have the ability to more easily store fat on the hips and legs, while men tend to accumulate fat around the abdomen to a higher extent,” says lead author Mathias Rask-Andersen, Ph.D. and postdoctoral researcher at the department of Immunology, Genetics and Pathology at Uppsala University. “This has been attributed to the effects of sex hormones such as estrogen. But the molecular mechanisms that control this phenomenon are fairly unknown.”
I am guessing that belly fat is the number one source of concern for people taking up exercise – or continuing it. So many fruitless hours have been spent on ‘ab-work’ like sit-ups and stomach crunches with little sign of success. It turns out that reduction of that ‘spare tire’ is far less complicated than many suppose. Simple, but not obvious.
Summary: According to researchers, interleukin 6 plays a critical role in how exercise helps to reduce body fat. Source: Cell Press.
Some of you may have made a New Year’s resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 plays a critical role in this process, researchers report December 27 in the journal Cell Metabolism.
This graphical abstract shows that in abdominally obese people, exercise-mediated loss of visceral adipose tissue mass requires IL-6 receptor signaling. NeuroscienceNews.com image is credited to Wedell-Neergaard, Lehrskov, and Christensen, et al. / Cell Metabolism.
As expected, a 12-week intervention consisting of bicycle exercise decreased visceral abdominal fat in obese adults. But remarkably, this effect was abolished in participants who were also treated with tocilizumab, a drug that blocks interleukin-6 signaling and is currently approved for the treatment of rheumatoid arthritis. Moreover, tocilizumab treatment increased cholesterol levels regardless of physical activity.
“The take home for the general audience is ‘do exercise,’” says first author Anne-Sophie Wedell-Neergaard of the University of Copenhagen. “We all know that exercise promotes better health, and now we also know that regular exercise training reduces abdominal fat mass and thereby potentially also the risk of developing cardio-metabolic diseases.”
How many times have I written eat less; move more; live longer. Now comes the Cleveland Clinic with a study that virtually says those very words – only better.
Cleveland Clinic researchers have found that better cardiorespiratory fitness leads to longer life, with no limit to the benefit of aerobic fitness.
Researchers retrospectively studied 122,007 patients who underwent exercise treadmill testing at Cleveland Clinic between Jan. 1, 1991, and Dec. 31, 2014, to measure all-cause mortality relating to the benefits of exercise and fitness. The paper was published in the Journal of the American Medical Association Network Open.
The study found that increased cardiorespiratory fitness was directly associated with reduced long-term mortality, with no limit on the positive effects of aerobic fitness. Extreme aerobic fitness was associated with the greatest benefit, particularly in older patients (70 and older) and in those with hypertension.
“Aerobic fitness is something that most patients can control. And we found in our study there is no limit to how much exercise is too much,” said Wael Jaber, M.D., Cleveland Clinic cardiologist and senior author of the study. “Everyone should be encouraged to achieve and maintain high fitness levels.” Continue reading
A comprehensive worldwide study of alcohol use and its impact on health concludes that the safest level of consumption is zero. The Global Burden of Disease Study 2016 has calculated levels of alcohol use and its effects on health during 1990–2016 in 195 countries.
The research, which now features in the journal The Lancet, notes that in 2016, alcohol use was responsible for almost 3 million deaths globally.
Alcohol use was the main cause of death for people aged 15–49 that year, accounting for 12 percent of deaths in men of that age.
“Our findings,” says senior study author Dr. Emmanuela Gakidou, who currently works at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington in Seattle, “are consistent with other recent research, which found clear and convincing correlations between drinking and premature death, cancer, and cardiovascular problems.” Continue reading
One of my favorite songs as a kid in the 1940’s was “Don’t fence me in.”
Here are some of the lyrics:
Oh, give me land, lots of land under starry skies above
Don’t fence me in
Let me ride through the wide open country that I love
Don’t fence me in
It appears I still feel that way, particularly when it comes to exercise. Working out in the health club really turns me off.
A new report reveals that exposure to green space reduces the risk of type II diabetes, cardiovascular disease, premature death, preterm birth, stress, and high blood pressure.
Populations with higher levels of green space exposure are also more likely to report good overall health – according to global data involving more than 290 million people. Continue reading
There seems to be a lot of pro-plant based diet info coming out of late. The old ‘meat and potatoes’ diets we grew up on in the ’50’s are being viewed in some doubt. Attitudes change as we learn more about health benefits. While I don’t mean to equate smoking with eating meat, I remember when my first wife was pregnant with our daughter in the 1960’s she said she was going to quit smoking till the baby was born. I thought that seemed really extreme at the time. These days no sane mom-to-be would consider ‘lighting up.’
Vegetarian, especially vegan, diets are associated with better cardiovascular health, according to a new review published in the journal Progress in Cardiovascular Diseases.
Researchers with the Physicians Committee for Responsible Medicine looked at multiple clinical trials and observational studies and found strong and consistent evidence that plant-based dietary patterns can prevent and reverse atherosclerosis and decrease other markers of cardiovascular disease (CVD) risk, including blood pressure, blood lipids, and weight. Continue reading
Regular readers know what a big fan I am of Costco. So, at first glance my going there today and walking out without buying anything may seem bizarre. However, I didn’t go to shop. They had a wonderful promotion on – Free Healthy Heart Screening. It ran from 10:00 AM to 2:00PM. No appointment needed.
Their brochure said, “Cardiovascular diseases rank as America’s #1 killer, claiming the lives of 40.6 % of more than 2.3 million people.
“* 60.8 million Americans have some form of Cardiovascular disease.
“* On average, someone in the U.S. suffers from a stroke every 53 seconds. That means about 600,000 people have a new or recurrent stroke each year.
“* You can reduce your risk. ”
They also offered a consultation with the pharmacist after your screening.
Because I didn’t want to fast, I had the truncated screening – Total Cholesterol & HDL Cholesterol. If you fasted, you could get a full lipid panel, TC, HDL, LDL, Triglycerides TC/HDL ratio.
Here are my results: Blood Pressure: 119/58; Total Cholesterol: 173; HDL 78. My Total Cholesterol/HDL ratio is 2.2 which, like the rest of my numbers is Low Risk. Continue reading