In a new study from University of California San Diego School of Medicine, researchers have confirmed that patients taking statin medications had a 41 percent lower risk of in-hospital death from COVID-19. The findings were published July 15, 2021 in PLOS ONE and expand upon prior research conducted at UC San Diego Health in 2020.
Statins are commonly used to reduce blood cholesterol levels by blocking liver enzymes responsible for making cholesterol. They are widely prescribed: The Centers for Disease Control estimates that 93 percent of patients who use a cholesterol-lowering drug use a statin.
“When faced with this virus at the beginning of the pandemic, there was a lot of speculation surrounding certain medications that affect the body’s ACE2 receptor, including statins, and whether they may influence COVID-19 risk,” said Lori Daniels, MD, lead study author, professor and director of the Cardiovascular Intensive Care Unit at UC San Diego Health.
“At the time, we thought that statins may inhibit SARS-CoV-2 infection through their known anti-inflammatory effects and binding capabilities, which could potentially stop progression of the virus.”
Regular readers know that Alzheimer’s Disease and dementia are two of my major considerations in aging. To clarify: Dementia is not a disease but a group of different diseases characterized by the gradual worsening of cognitive abilities. Dementia is seen across all ethnic groups and increasingly so with advancing age. Among 65–69-year-olds, about 2 percent are afflicted, with this figure doubling for every five years of age. Alzheimer’s accounts for 60 to 80 percent of cases.