I am guessing that belly fat is the number one source of concern for people taking up exercise – or continuing it. So many fruitless hours have been spent on ‘ab-work’ like sit-ups and stomach crunches with little sign of success. It turns out that reduction of that ‘spare tire’ is far less complicated than many suppose. Simple, but not obvious.
Summary: According to researchers, interleukin 6 plays a critical role in how exercise helps to reduce body fat. Source: Cell Press.
Some of you may have made a New Year’s resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 plays a critical role in this process, researchers report December 27 in the journal Cell Metabolism.
This graphical abstract shows that in abdominally obese people, exercise-mediated loss of visceral adipose tissue mass requires IL-6 receptor signaling. NeuroscienceNews.com image is credited to Wedell-Neergaard, Lehrskov, and Christensen, et al. / Cell Metabolism.
As expected, a 12-week intervention consisting of bicycle exercise decreased visceral abdominal fat in obese adults. But remarkably, this effect was abolished in participants who were also treated with tocilizumab, a drug that blocks interleukin-6 signaling and is currently approved for the treatment of rheumatoid arthritis. Moreover, tocilizumab treatment increased cholesterol levels regardless of physical activity.
“The take home for the general audience is ‘do exercise,’” says first author Anne-Sophie Wedell-Neergaard of the University of Copenhagen. “We all know that exercise promotes better health, and now we also know that regular exercise training reduces abdominal fat mass and thereby potentially also the risk of developing cardio-metabolic diseases.”
I have posted several times on the danger of a big waistline. Check out my Page – How dangerous is a big belly? for more details. Now comes a fresh new study from down under on it.
People with a normal Body Mass Index (BMI) who carry their weight around the middle are at the highest risk of death from any cause and cardiovascular causes compared to those who are obese according to BMI but carry their weight elsewhere, a new study co-led by University of Sydney researchers shows.
Published this week in the Annals of Internal Medicine, the study shows that normal weight people who carry fat around the middle of their body are 22 per cent more likely to die from any cause and a 25 per cent higher risk for death from cardiovascular causes compared to those who are classified as normal weight without carrying fat centrally.
The University of Sydney’s Associate Professor Emmanuel Stamatakis from the Charles Perkins Centre and School of Public Health co-led the research and says the study shows that diagnosis of obesity cannot solely rely on a person’s BMI.
Belly fat is very bad. It can literally kill you. I have a Page on it – What are the dangers of a big waistline? that contains a number of articles spelling out chapter and verse on its dangers.
Now comes Harvard Health Publications with more info on this weighty subject.
“Though the term might sound dated, “middle-age spread” is a greater concern than ever. As people go through their middle years, their proportion of fat to body weight tends to increase — more so in women than men. Extra pounds tend to park themselves around the midsection.
“At one time, we might have accepted these changes as an inevitable fact of aging. But we’ve now been put on notice that as our waistlines grow, so do our health risks. Abdominal, or visceral fat is of particular concern because it’s a key player in a variety of health problems — much more so than subcutaneous fat, the kind you can grasp with your hand. Visceral fat, on the other hand, lies out of reach, deep within the abdominal cavity, where it pads the spaces between our abdominal organs.
“Visceral fat has been linked to metabolic disturbances and increased risk for cardiovascular disease and type 2 diabetes. In women, it is also associated with breast cancer and the need for gallbladder surgery.
Are you pear-shaped or apple-shaped? Continue reading
On the premise that one picture is worth a thousand words, herewith a killer graphic on burning off your belly fat.
Belly fat is no laughing matter at least to the possessor. To read further, check out:
What About Belly Fat – Central Obesity?
How Dangerous is a Big Belly?
What are the best and worst foods for belly fat?
How Bad is Extra Belly Fat?