Category Archives: mild cognitive impairment

Which leisure activities are linked to lower risk of dementia?

Leisure activities, such as reading a book, doing yoga and spending time with family and friends, may help lower the risk of dementia, according to a new meta-analysis published in the August 10, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. The meta-analysis reviewed available studies on the effects of cognitive activities, physical activities, and social activities and the risk of dementia.

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“Previous studies have shown that leisure activities were associated with various health benefits, such as a lower cancer risk, a reduction of atrial fibrillation, and a person’s perception of their own well-being,” said study author Lin Lu, PhD, of Peking University Sixth Hospital in Beijing, China. “However, there is conflicting evidence of the role of leisure activities in the prevention of dementia. Our research found that leisure activities like making crafts, playing sports or volunteering were linked to a reduced risk of dementia.”

The meta-analysis involved a review of 38 studies from around the world involving a total of more than 2 million people who did not have dementia. The participants were followed for at least three years.

Participants provided information on their leisure activities through questionnaires or interviews. Leisure activities were defined as those in which people engaged for enjoyment or well-being and were divided into mental, physical and social activities.

During the studies, 74,700 people developed dementia.

After adjusting for factors such as age, sex and education, researchers found that leisure activities overall were linked to a reduced risk of dementia. Those who engaged in leisure activities had a 17% lower risk of developing dementia than those who did not engage in leisure activities.

Mental activity mainly consisted of intellectual activities and included reading or writing for pleasure, watching television, listening to the radio, playing games or musical instruments, using a computer and making crafts. Researchers found that people who participated in these activities had a 23% lower risk of dementia.

Physical activities included walking, running, swimming, bicycling, using exercise machines, playing sports, yoga, and dancing. Researchers found that people who participated in these activities had a 17% lower risk of dementia.

Social activities mainly referred to activities that involved communication with others and included attending a class, joining a social club, volunteering, visiting with relatives or friends, or attending religious activities. Researchers found that people who participated in these activities had a 7% lower risk of dementia.

“This meta-analysis suggests that being active has benefits, and there are plenty of activities that are easy to incorporate into daily life that may be beneficial to the brain,” Lu said. “Our research found that leisure activities may reduce the risk of dementia. Future studies should include larger sample sizes and longer follow-up time to reveal more links between leisure activities and dementia.”

A limitation of the study was that people reported their own physical and mental activity, so they may not have remembered and reported the activities correctly.

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How Diabetes and Obesity Affect the Brain

With more than 30 million Americans diagnosed with diabetes, and another 87 million diagnosed with obesity, both conditions have become national epidemics. 

The two diseases cause a number of complications, including neuropathy, which causes damage to the peripheral nerves. Neuropathy is characterized by numbness or tingling and can sometimes be accompanied by pain. 

Brian Callaghan, M.D., the Fovette E. Dush associate professor of neurology, has sounded an alarm through his recent clinical research, which has demonstrated that, in addition to peripheral nerve damagediabetes and obesity can also cause cognitive dysfunction, effecting thinking, reasoning or memory. 

Here, Callaghan discusses his latest work and ways to identify and treat the condition:

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Heart Attack Patients with Mild Cognitive Impairment Get Fewer Treatments

I guess this would be an example of the old adage, “When it rains, it pours.”

A new study finds people who have mild cognitive impairment (MCI), which lies on the continuum of cognitive decline between normal cognition and dementia, are less likely to receive proven heart attack treatment in the hospital.

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Researchers found no evidence that those with MCI would derive less benefit from evidence-based treatment that’s offered to their cognitively normal peers who have heart attacks, says lead author Deborah Levine, M.D., MPH.

“Patients should get the treatments they would want if they were properly informed,” says Levine, an associate professor of internal medicine and neurology at Michigan Medicine.

Some people with thinking, memory and language problems have MCI. Unlike dementia, which severely interferes with daily functioning and worsens over time, MCI does not severely interfere with daily functioning and might not worsen over time. Although people with MCI have an increased risk of developing dementia, it’s not an inevitable next step, Levine says.

“While some may progress to dementia, many will persist in having MCI, and a few will actually improve and revert to normal cognition,” says Levine, also a member of the University of Michigan Institute for Healthcare Policy and Innovation. “Many older adults with MCI live years with good quality of life, and so face common health risks of aging like heart attack and stroke.

“Clinicians, patients and families might be overestimating the risk of dementia after a mild cognitive impairment diagnosis even without realizing it. These older adults with MCI should still receive evidence-based treatments when indicated.” Continue reading

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