I have written numerous times about the dangers and negative effects of obesity. You can check out previous posts by typing in o b e s i t y in the search box on the right.
New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells).
Published Dec. 27, the study was led by researchers at the Cincinnati Children’s Cancer and Blood Diseases Institute. Conducted largely in genetic models of obese mice, it shows obesity causes durable and harmful changes to the hematopoietic stem cell compartment – the blood-making factory in our bodies. Continue reading
When it rains it pours. As if it weren’t difficult enough to be a senior citizen, it turns out that Type 2 diabetes adds a further level of complexity.
Though seniors with Type 2 diabetes (T2D) tend to have normal or higher bone density than their peers, researchers have found that they are more likely to succumb to fractures than seniors without T2D. In a new study published in the Journal of Bone and Mineral Research, researchers from Hebrew SeniorLife’s Institute for Aging Research found older adults with Type 2 diabetes had deficits in cortical bone–the dense outer surface of bone that forms a protective layer around the internal cavity– compared to non-diabetics. The findings suggest that the microarchitecture of cortical bone may be altered in seniors with T2D and thereby place them at increased risk of fracture.
Participants in this study included over 1,000 member of the Framingham Study who were examined over a period of 3 years. High resolution scanning allowed researchers to determine that many older adults with diabetes had weakness specific to cortical bone microarchitecture that cannot be measured by standard bone density testing.
Osteoporotic fractures are a significant public health problem that can lead to disability, decreased quality of life, and even death – not to mention significant health care costs. Risk of fracture is even greater in adults with T2D, including a 40 – 50% increased risk of hip fracture – the most serious of osteoporotic fractures.
“Fracture in older adults with Type 2 diabetes is a highly important public health problem and will only increase with the aging of the population and growing epidemic of diabetes. Our findings identify skeletal deficits that may contribute to excess fracture risk in older adults with diabetes and may ultimately lead to new approaches to improve prevention and treatment,” said Dr. Elizabeth Samelson, lead author of the study.
Researchers hope that novel studies such as this will help to revolutionize the area of bone health, especially for older adults. It is important to follow screening guidelines for bone density testing, but better understanding of all the factors that affect bone strength and the tendency to fracture is needed.
While eat less; move more; live longer is the mantra of this blog, I hasten to add that strength training should be an integral part of that move more aspect. Harvard HEALTHbeat has come out with a new publication on strength and power training.
Here’s what Harvard has to say on the subject: “Most of us know that strength training (with free weights, weight machines, or resistance bands) can help build and maintain muscle mass and strength. What many of us don’t know is that strong muscles lead to strong bones. And strong bones can help minimize the risk of fracture due to osteoporosis.
“A combination of age-related changes, inactivity, and poor nutrition conspire to steal bone mass at the rate of 1% per year after age 40. As bones grow more fragile and susceptible to fracture, they are more likely to break after even a minor fall or a far less obvious stress, such as bending over to tie a shoelace.
“Osteoporosis should be a concern for all of us. Eight million women and two million men in the United States have osteoporosis. It is now responsible for more than two million fractures a year, and experts expect that number will rise. Hip fractures are usually the most serious. Six out of 10 people who break a hip never fully regain their former level of independence. Even walking across a room without help may be impossible.”
I have written several posts on osteoporosis. You can read further on the subject here: What Can I do to Prevent Osteoporosis? An Early Sign of Osteoporosis? Are Men Vulnerable to Osteoporosis as Well as Women? Continue reading
Thought you might enjoy this. I certainly did.
Infographic created by Vapester .
Dem bones, dem bones, dem dry bones.
Now hear the word of the Lord.
Those lyrics from an old spiritual have been running through my head since I started reading about osteoporosis and our bones.
More women are affected by osteoporosis than men, but we guys are definitely vulnerable, especially as we age.
Facts and statistics:
- Up to one in four men over age 50 will break a bone due to osteoporosis.
- Approximately two million American men already have osteoporosis. About 12 million more are at risk.
- Men older than 50 are more likely to break a bone due to osteoporosis than they are to get prostate cancer.
- Each year, about 80,000 men will break a hip.
- Men are more likely than women to die within a year after breaking a hip. This is due to problems related to the break.
- Men can break bones in the spine or break a hip, but this usually happens at a later age than women.
Here’s what the National Osteoporosis Foundation has to say about it:
I wanted to include this for two reasons, first, it has excellent information about our bones and a lot of people are pretty ignorant about them, myself included. Second, I thought it was really beautiful, very creatively constructed.
Let’s face it most people take their bones for granite (sorry, couldn’t resist it). But, it is important to realize that we need to work to strengthen our bones, too. Make sure you include weight-bearing exercise in your life. It will keep your bones strong.