Link found between physical function and cardiovascular disease risk in older adults, according to new study in the Journal of the American Heart Association
Among people older than age 65 who were assessed using a short physical function test, having lower physical function was independently associated with a greater risk of developing heart attack, heart failure and stroke, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.
The Short Physical Performance Battery (SPPB) used in this study is considered a measure of physical function, which includes walking speed, leg strength and balance. This study examined physical function, which is different from physical fitness.
“While traditional cardiovascular disease risk factors such as high blood pressure, high cholesterol, smoking or diabetes are closely linked to cardiovascular disease, particularly in middle-aged people, we also know these factors may not be as predictive in older adults, so we need to identify nontraditional predictors for older adults,” said study senior author Kunihiro Matsushita, M.D., Ph.D., an associate professor in the department of epidemiology at the Johns Hopkins Bloomberg School of Public Health and the Division of Cardiology at the Johns Hopkins School of Medicine in Baltimore. “We found that physical function in older adults predicts future cardiovascular disease beyond traditional heart disease risk factors, regardless of whether an individual has a history of cardiovascular disease.”
Our visual perception of the world is often thought of as relatively stable. However, like all of our cognitive functions, visual processing is shaped by our experiences. During both development and adulthood, learning can alter visual perception. For example, improved visual discrimination of similar patterns is a learned skill critical for reading. In a new research study published in Current Biology, scientists have now discovered the neuronal changes that occur during learning to improve discrimination of closely related visual images.
This study, led by first author Dr. Joseph Schumacher and senior author Dr. David Fitzpatrick at the Max Planck Florida Institute for Neuroscience, establishes a transformative approach to studying perceptual learning in the brain. Researchers imaged the activity of large numbers of single neurons over days to track the changes that occur while a visual discrimination task is learned, performing these experiments in a novel animal model, the tree shrew.
Researchers from a USC-led consortium have discovered 15 “hot spots” in the genome that either speed up brain aging or slow it down — a finding that could provide new drug targets to resist developmental delays, Alzheimer’s disease and other degenerative brain disorders, according to the University of Southern California (USC).
“The big game-changer here is discovering locations on the chromosome that speed up or slow down brain aging in worldwide populations. These can quickly become new drug targets,” said Paul Thompson of USC, a lead author on the study and the co-founder and director of the ENIGMA Consortium. “Through our AI4AD [Artificial Intelligence for Alzheimer’s Disease] initiative we even have a genome-guided drug repurposing program to target these and find new and existing drugs that help us age better.”
A universal sign of motherhood is the lullaby. The world over, mothers sing to their babies, whether Twinkle Twinkle Little Star, their favorite song from the radio, or even random notes. This universality makes the simple lullaby a great window into the human mind. In a new study, cognitive neuroscientists found that lullabies soothe both moms and babies simultaneously, while playsongs increase babies’ attention and displays of positive emotion toward their mothers.
The behavioral implications of music are vast, says Laura Cirelli of the University of Toronto Mississauga, who is presenting the new work on maternal singing at the 25th meeting of the Cognitive Neuroscience Society (CNS) in Boston today. “Infant brains must be able to track auditory events in a predictive manner to make sense of music,” she explains, and many complex things are going on in their brains to make that possible.
From infancy to old age, music demands much from the human brain. Learning more about how we process music is helping scientists better understand perception, multisensory integration, and social coordination across the lifespan. Technological advancements – for example, more portable electroencephalography (EEG) and electrophysiology set-ups and- are allowing cognitive neuroscientists to study music in a variety of situations, from mother-child interactions to live concert halls.
Having trouble paying attention? MIT neuroscientists may have a solution for you: Turn down your alpha brain waves. In a new study, the researchers found that people can enhance their attention by controlling their own alpha brain waves based on neurofeedback they receive as they perform a particular task.
Anne Trafton of the MIT New Service writes, the study found that when subjects learned to suppress alpha waves in one hemisphere of their parietal cortex, they were able to pay better attention to objects that appeared on the opposite side of their visual field. This is the first time that this cause-and-effect relationship has been seen, and it suggests that it may be possible for people to learn to improve their attention through neurofeedback.
“There’s a lot of interest in using neurofeedback to try to help people with various brain disorders and behavioral problems,” says Robert Desimone, director of MIT’s McGovern Institute for Brain Research. “It’s a completely noninvasive way of controlling and testing the role of different types of brain activity.”
It’s unknown how long these effects might last and whether this kind of control could be achieved with other types of brain waves, such as beta waves, which are linked to Parkinson’s disease. The researchers are now planning additional studies of whether this type of neurofeedback training might help people suffering from attentional or other neurological disorders.
As regular readers know, I am very sensitive to cognitive impairment, having lost three close family members to Alzheimer’s and dementia. So I was very happy to come across this list of recommendations for building up our mental muscles and reducing our chances of contracting Alzheimer’s from the Alzheimer’s Association.
“Research on cognitive decline is still evolving,” said Theresa Hocker, president and CEO of the Alzheimer’s Association – North Central Texas Chapter. “But there are actions people can take. Certain healthy behaviors known to combat cancer, cardiovascular disease and diabetes also may reduce the risk of cognitive decline. These include staying mentally active, engaging in regular physical activity, and eating a heart-healthy diet that benefits your body and your brain.”
1. Break a sweat. Engage in regular cardiovascular exercise that elevates your heart rate and increases blood flow to the brain and body. Several studies have found an association between physical activity and reduced risk of cognitive decline.
2. Hit the books. Formal education in any stage of life will help reduce your risk of cognitive decline and dementia. For example, take a class at a local college, community center or online.
3. Butt out. Evidence shows that smoking increases risk of cognitive decline. Quitting smoking can reduce that risk to levels comparable to those who have not smoked. Continue reading →
When we train the reaching for and grasping of objects, we also train our brain. In other words, this action brings about changes in the connections of a certain neuronal population in the red nucleus, a region of the midbrain. Researchers at the University of Basel’s Biozentrum have discovered this group of nerve cells in the red nucleus. They have also shown how fine motor tasks promote plastic reorganization of this brain region. The results of the study have been published recently in Nature Communications.
Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan’s research group at the Biozentrum, University of Basel, has investigated the red nucleus, a region of the midbrain that controls fine motor movement, and identified a new population of nerve cells which changes when fine motor coordination is trained. The more that grasping is practiced, the more the connections between the neurons of this group of nerve cells are strengthened. Continue reading →
I really wanted to reproduce this just because the illusion seemed so cool to me. I don’t know that you can benefit from in any way, but to enjoy it. Follow the directions in the caption – and enjoy.
Summary: Researchers report the same subset of neurons encode actual and illusory flow motion, supporting the concept Jan Purkinje proposed 150 years ago, that “illusions contain visual truth”.Source: SfN.
A study of humans and monkeys published in Journal of Neuroscience has found the same subset of neurons encode actual and illusory complex flow motion. This finding supports, at the level of single neurons, what the Czech scientist Jan Purkinje surmised 150 years ago: “Illusions contain visual truth.”
Fixate the black dot and move your head towards and away from the image and you should perceive the rings rotating. NeuroscienceNews.com image is credited to Junxiang Luo.
The Pinna-Brelstaff figure is a static image of rings that appear to rotate clockwise as one moves toward and counterclockwise as one moves away from the figure. Having previously identified particular parts of the human brain that represent the Pinna illusion, Junxiang Luo and colleagues at the Institute of Neuroscience, Chinese Academy of Sciences first confirmed that male rhesus macaques likely perceive the illusion similarly to people.
The researchers then recorded activity from individual neurons in the previously identified brain regions, and discovered cells that signal the illusory motion similarly to actual motion. A delay of about 15 milliseconds enables the brain to register the illusory motion as if it was real.
This study provides new insights into how the brain grapples with the continual mismatch between perception and reality.
Researchers at the Montreal Neurological Institute and Hospital (The Neuro) of McGill University examined the effects of aging on neuroplasticity in the primary auditory cortex, the part of the brain that processes auditory information. Neuroplasticity refers to the brain’s ability to modify its connections and function in response to environmental demands, an important process in learning.
Plasticity in the young brain is very strong as we learn to map our surroundings using the senses. NeuroscienceNews.com image is in the public domain.
Plasticity in the young brain is very strong as we learn to map our surroundings using the senses. As we grow older, plasticity decreases to stabilize what we have already learned. This stabilization is partly controlled by a neurotransmitter called gamma-Aminobutyric acid (GABA), which inhibits neuronal activity. This role of GABA was discovered by K.A.C. Elliot and Ernst Florey at The Neuro in 1956. Continue reading →
Music is one of the great joys of my life. I have a bluetooth speaker on my bike and I listen to music on my daily rides. My iPhone has about 15 gigabytes of jazz, classics and classic rock so I have the entire spectrum available. Consuming music, however, is not the same as producing it.
Different processes occur in the brains of jazz and classical pianists while playing the same piece of music, researchers report in Neuroscience News.
Keith Jarret, world-famous jazz pianist, once answered in an interview when asked if he would ever be interested in doing a concert where he would play both jazz and classical music: “No, that’s hilarious. […] It’s like a chosen practically impossible thing […] It’s [because of] the circuitry. Your system demands different circuitry for either of those two things.” Where non-specialists tend to think that it should not be too challenging for a professional musician to switch between styles of music, such as jazz and classical, it is actually not as easy as one would assume, even for people with decades of experience.
Herewith more good news on the connection between exercise and mental capacity. Eat less; move more; live longer – and maybe think better.
A 10-minute, one-time burst of exercise can measurably boost your brain power, at least temporarily, researchers at Western University in London, Canada, have found.
While other studies have showed brain-health benefits after 20-minutes of a single-bout of exercise, or following commitment to a long-term (24-week) exercise program, this research suggests even 10 minutes of aerobic activity can prime the parts of the brain that help us problem-solve and focus.
“Some people can’t commit to a long-term exercise regime because of time or physical capacity,” said Kinesiology Prof. Matthew Heath, who is also a supervisor in the Graduate Program in Neuroscience and, with master’s student Ashna Samani, conducted the study. “This shows that people can cycle or walk briskly for a short duration, even once, and find immediate benefits.” Continue reading →
As regular readers know, I think we should all exercise regularly to keep our bodies and brains functioning at their best levels. It’s nice to see that the phrase use it or lose it has value on more than one level.
Mount Sinai researchers have found a positive relationship between the brain network associated with working memory—the ability to store and process information relevant to the task at hand—and healthy traits such as higher physical endurance and better cognitive function.
These traits were associated with greater cohesiveness of the working memory brain network while traits indicating sub-optimal cardiovascular and metabolic health, and sub-optimal health habits including binge drinking and regular smoking, were associated with less cohesive working memory networks.
This is the first study to establish the link between working memory and physical health and lifestyle choices.
The results of the study were published online in Molecular Psychiatry on Tuesday, December 5, 2017.
The research team took brain scans of 823 participants in the Human Connectome Project (HCP), a large brain imaging study funded by the National Institutes of Health, while they performed a task involving working memory, and extracted measures of brain activity and connectivity to create a brain map of working memory. The team then used a statistical method called sparse canonical correlation to discover the relationships between the working memory brain map and 116 measures of cognitive ability, physical and mental health, personality, and lifestyle choices. They found that cohesiveness in the working memory brain map was positively associated with higher physical endurance and better cognitive function. Physical traits such as high body mass index, and suboptimal lifestyle choices including binge alcohol drinking and regular smoking, had the opposite association.
“Working memory accounts for individual differences in personal, educational, and professional attainment,” said Sophia Frangou, MD, PhD, Professor of Psychiatry at the Icahn School of Medicine at Mount Sinai. “Working memory is also one of the brain functions that is severely affected by physical and mental illnesses. Our study identified factors that can either support or undermine the working memory brain network. Our findings can empower people to make informed choices about how best to promote and preserve brain health.”
There is something universal about what occurs in the brain when it processes stories, regardless of a person’s origin or language, according to a study at the University of Southern California.
New brain research by USC scientists shows that reading stories is a universal experience that may result in people feeling greater empathy for each other, regardless of cultural origins and differences.
Human brain cell
And in what appears to be a first for neuroscience, USC researchers have found patterns of brain activation when people find meaning in stories, regardless of their language. Using functional MRI, the scientists mapped brain responses to narratives in three different languages — English, Farsi and Mandarin Chinese.
The USC study opens up the possibility that exposure to narrative storytelling can have a widespread effect on triggering better self-awareness and empathy for others, regardless of the language or origin of the person being exposed to it.
“Even given these fundamental differences in language, which can be read in a different direction or contain a completely different alphabet altogether, there is something universal about what occurs in the brain at the point when we are processing narratives,” said Morteza Dehghani, the study’s lead author and a researcher at the Brain and Creativity Institute at USC. Continue reading →
Eat less; move more; live longer remains the mantra of this blog. So, it is always useful to learn more about how various inputs like food and exercise impact the brain. Here is some fresh info on walnuts from Beth Israel Deaconess Medical Center.
Double-blind test bolsters observational data that walnuts promote feelings of fullness.
Results provide a quantitative measure for testing other compounds’ ability to control appetite, including potential medications for the treatment of obesity.
Fascinating how walnuts also suggest the shape of the brain.
Packed with nutrients linked to better health, walnuts are also thought to discourage overeating by promoting feelings of fullness. Now, in a new brain imaging study, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that consuming walnuts activates an area in the brain associated with regulating hunger and cravings. The findings, published online in the journal Diabetes, Obesity and Metabolism, reveal for the first time the neurocognitive impact these nuts have on the brain.Continue reading →