Category Archives: bone marrow

Obesity affects bone health – Study

I have written numerous times about the dangers and negative effects of obesity. You can check out previous posts by typing in o b e s i t y in the search box on the right.

New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells).

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Published Dec. 27, the study was led by researchers at the Cincinnati Children’s Cancer and Blood Diseases Institute. Conducted largely in genetic models of obese mice, it shows obesity causes durable and harmful changes to the hematopoietic stem cell compartment – the blood-making factory in our bodies. Continue reading

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Bad to the Bone – WebMD

With apologies to George Thorogood, whose Bad to the Bone is a true rock classic, you really don’t want to be bad to your bones.

WebMD has produced a slideshow demonstrating things we do and don’t do that damage our bones. Our bones are as strong as cast iron yet remains as light as wood. Keep in mind that our bones are not all solid. The outside is solid surrounded by a few small canals. The inside, however, looks like a honeycomb.

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The way we strengthen our bones is with weight-bearing exercise and good diet choices. As a bike rider, I am very aware of this. My regular riding is super cardio exercise, but does nothing for my bones. Not long ago, Tour de France riders, started integrating weight lifting with their workouts as they were coming down with osteoporosis.

WebMD offers eleven examples in a slide show that is worth checking out.

Here are a few examples in case you don’t have time right now. Skip that next pitcher of Margaritas. “When you’re out with friends, one more round might sound like fun. But to keep bone loss in check, you should limit the amount of alcohol you drink. No more than one drink a day for women and two for men is recommended. Alcohol can interfere with how your body absorbs calcium.”

I have written a Page about the damage smoking does and it turns out smoking damages your bones, too. “When you regularly inhale cigarette smoke, your body can’t form new healthy bone tissue as easily. The longer you smoke, the worse it gets.
Smokers have a greater chance of breaks and take longer to heal. But if you quit, you can lower these risks and improve your bone health, though it might take several years.”

See what you can do to be good to your bones.

Tony

 

 

 

 

 

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Bone Marrow Fat Tissue Secretes Hormone that Helps Body Stay Healthy

“Bone marrow adipose tissue has traditionally had a bad reputation because of its relationship to decreased bone mass but we now know that adipose tissue within marrow goes beyond the bone and also serves as an endocrine organ that can influence metabolism,” says co-lead author William Cawthorn, Ph.D., a U-M postdoctoral fellow in the MacDougald lab.

Cooking with Kathy Man

It has been known for its flavorful addition to soups and as a delicacy for dogs but bone marrow fat may also have untapped health benefits, new research finds.

A University of Michigan-led study shows that the fat tissue in bone marrow is a significant source of the hormone adiponectin, which helps maintain insulin sensitivity, break down fat, and has been linked to decreased risk of cardiovascular disease, diabetes, and obesity-associated cancers. The findings appear in today’s online-ahead-of-print issue of Cell Metabolism.

Bone marrow adipose tissue has primarily been associated with negative health effects, most notably because of a documented relationship to reduced bone mass and increased risks of fractures and osteoporosis. The new study however – which included people with anorexia, patients undergoing chemotherapy, rabbits and mice – suggests that this type of fat may also have benefits.

“These findings are significant because we’ve found that bone marrow adipose…

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