Exercise may reduce negative effects of unhealthy sleep duration on longevity

Sleep duration per night was classified as short (less than six hours), normal (six to eight hours) or long (more than eight hours). Total volume of physical activity was divided into tertiles (low, intermediate, high). Moderate to vigorous physical activity was classified as meeting World Health Organization (WHO) guidelines or not.2 Mortality data were collected from death registries. The primary outcome was all-cause death. The secondary endpoints were death due to cardiovascular disease and death due to cancer.

The average age of participants was 62 years and 56% were women. During a median follow up of seven years, 3,080 participants died – 1,074 from cardiovascular disease and 1,871 from cancer.

The researchers examined how physical activity influenced sleep’s impact on mortality – first looking at the volume of activity and second at moderate to vigorous physical activity. The analyses were adjusted for factors that could influence the relationship including age, sex, ethnicity, deprivation, education level, season of sleep measurement, body mass index, diet, smoking, alcohol intake and shift work.

Regarding the volume of activity, in those with low amounts, short and long sleep were associated with 16% and 37% raised risks of all-cause death, respectively. In participants with intermediate amounts of exercise, only short sleep was detrimental, with a 41% raised likelihood of all-cause death. In those with a high amount of exercise, sleep duration was not linked with risk of death. For cardiovascular death, short sleepers with a low volume of exercise had a 69% elevated risk, which disappeared when exercise increased to moderate or high volumes. For cancer death, long sleepers with low amounts of exercise had a 21% raised risk which disappeared with moderate or high volumes of exercise.

Similar results were found for moderate to vigorous physical activity. In participants not meeting the WHO recommendations, short and long sleep were associated with 31% and 20% raised risks of all-cause death, respectively. These risks disappeared in those meeting the WHO advice. For cardiovascular death, short sleepers who failed to meet the advice on intensity of exercise had a 52% elevated risk, which disappeared in those achieving the recommendations. For cancer death, long sleepers not meeting the advice had a 21% raised risk which disappeared in those following the WHO guidance.

Dr. Zhang said: “Our findings suggest that health promotion efforts targeting both physical activity and sleep duration may be more effective in preventing or delaying premature death in middle-aged
and older adults than focusing on one behaviour alone. In an ideal scenario, people would always get healthy amounts of both sleep and physical activity. However, our study indicates that getting sufficient exercise may partially offset the detrimental impact of missing a good night’s sleep.”

1 Comment

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One response to “Exercise may reduce negative effects of unhealthy sleep duration on longevity

  1. As a teenager I remember those ice cream cartons in the freezer… “Cold comfort”

    Liked by 1 person

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