Exercise alters brain chemistry to protect aging synapses

When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition, a UC San Francisco study has found.

This protective impact was found even in people whose brains at autopsy were riddled with toxic proteins associated with Alzheimer’s and other neurodegenerative diseases.

Riding with my dog on Lake Shore Drive in Chicago. The annual Bike the Drive when the city closes the Drive to autos and lets us bike rides ‘have a turn.’

“Our work is the first that uses human data to show that synaptic protein regulation is related to physical activity and may drive the beneficial cognitive outcomes we see,” said Kaitlin Casaletto, PhD, an assistant professor of neurology and lead author on the study, which appears in the January 7 issue of Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.

The beneficial effects of physical activity on cognition have been shown in mice but have been much harder to demonstrate in people.

3 Comments

Filed under Uncategorized

3 responses to “Exercise alters brain chemistry to protect aging synapses

  1. I believe exercise is a very important thing as we age. I have been walking 4-5 miles every day and what a difference it has made in my mental state of mind. It defiantly helped me handle the stress of COVID. Now I can’t stop. 🙂 My heart app said I averaged 4 miles a day in 2021. So that is where the bar is set for 2022!!

    Like

  2. Love this! I don’t know what I’d do if I didn’t keep moving!

    Like

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s