Motivation depends on how brain processes fatigue

“We found that people’s willingness to exert effort fluctuated moment by moment, but gradually declined as they repeated a task over time,” says Tanja Müller, first author of the study, based at the University of Oxford. “Such changes in the motivation to work seem to be related to fatigue – and sometimes make us decide not to persist.”

The team tested 36 young, healthy people on a computer-based task, where they were asked to exert physical effort to obtain differing amounts of monetary rewards. The participants completed more than 200 trials and in each, they were asked if they would prefer to ‘work’ – which involved squeezing a grip force device – and gain the higher rewards offered, or to rest and only earn a small reward.

The team built a mathematical model to predict how much fatigue a person would be feeling at any point in the experiment, and how much that fatigue was influencing their decisions of whether to work or rest.

While performing the task, the participants also underwent an MRI scan, which enabled the researchers to look for activity in the brain that matched the predictions of the model.

They found areas of the brain’s frontal cortex had activity that fluctuated in line with the predictions, while an area called the ventral striatum signalled how much fatigue was influencing people’s motivation to keep working.

“This work provides new ways of studying and understanding fatigue, its effects on the brain, and on why it can change some people’s motivation more than others” says Dr Matthew Apps, senior author of the study, based at the University of Birmingham’s Centre for Human Brain Health. “This helps begin to get to grips with something that affects many patients lives, as well as people while at work, school, and even elite athletes.


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2 responses to “Motivation depends on how brain processes fatigue

  1. Ssenyonga Edward

    Thank you for your research and update extended to us.I am Ssenyonga Edward here in Kampala Uganda East Africa.I am depressed and I request you to help in order i regain my peace of mind.Thank you Sir.Ssenyonga Edward.

    On Tue, Aug 10, 2021, 7:17 AM Health Secrets of a SuperAger wrote:

    > Tony posted: ” How do we decide whether or not an activity which requires > work is ‘worth the effort?’ Researchers at the University of Birmingham & > University of Oxford have shown that the willingness to work is not static, > and depends upon the fluctuating rhythms ” >

    Liked by 1 person

    • Thanks very much for your confidence in me, but I have to tell you that I am a journalist, not a medical practicioner. I am not equipped to handle medical problems.


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