Research over the last decade has shown that loneliness is an important determinant of health. It is associated with considerable physical and mental health risks and increased mortality. Previous studies have also shown that wisdom could serve as a protective factor against loneliness. This inverse relationship between loneliness and wisdom may be based in different brain processes.
In a study published in the March 5, 2021 online edition of Cerebral Cortex, researchers at University of California San Diego School of Medicine found that specific regions of the brain respond to emotional stimuli related to loneliness and wisdom in opposing ways.
“We were interested in how loneliness and wisdom relate to emotional biases, meaning how we respond to different positive and negative emotions,” said Jyoti Mishra, PhD, senior author of the study, director of the NEATLabs and assistant professor in the Department of Psychiatry at UC San Diego School of Medicine.