Gut Microbiome Implicated in Healthy Aging and Longevity

The gut microbiome is an integral component of the body, but its importance in the human aging process is unclear. Institute for Systems Biology (ISB) researchers and their collaborators have identified distinct signatures in the gut microbiome that are associated with either healthy or unhealthy aging trajectories, which in turn predict survival in a population of older individuals. The work was just published in the journal Nature Metabolism,

Data from over 9,000 people reveal a distinct gut microbiome signature that is associated with healthy aging and survival in the latest decades of life.

The research team analyzed gut microbiome, phenotypic and clinical data from over 9,000 people – between the ages of 18 and 101 years old – across three independent cohorts. The team focused, in particular, on longitudinal data from a cohort of over 900 community-dwelling older individuals (78-98 years old), allowing them to track health and survival outcomes.

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2 responses to “Gut Microbiome Implicated in Healthy Aging and Longevity

  1. As I read this I recalled a comment my father made 15 years ago. He was 79 at the time and said, “I shouldn’t feel old, I’m not 80 years old yet. Not at almost 94 years he lives on his own, drives his own car yet, sometimes 120 km in a day, and reads voraciously. He also emails regularly as he has difficulty hearing so he has no phone.

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