As we age, the strength and size of our muscles tend to decrease. This loss of muscle mass and function, called sarcopenia, is associated with decreased independence and reduced quality of life. Staying active (and purposefully incorporating muscle-strengthening exercises) is essential, but emerging data suggest that nourishing our gut microbes could be important as well.

The Gut-Muscle Connection: The trillions of bacteria and other microbes that live in our guts are intimately intertwined with our metabolism. These microscopic inhabitants play roles in digestion, nutrient absorption, and amino acid synthesis, and are also involved in maintaining the integrity of the intestinal lining so invading organisms, unwanted food components, and the wrong microbial products cannot slip through. Studying the role of the gut microbiome in health is challenging, but research suggests that the make-up of our personal inner world of tiny organisms could play a role in our risk for a number of common diseases and conditions, including obesity, diabetes, and cardiovascular disease. “Emerging research in mice and preliminary human studies suggest there may also be a connection between our gut microbiome and our muscles,” says Michael Lustgarten, PhD, a scientist in the Nutrition, Exercise Physiology, and Sarcopenia laboratory at the Human Nutrition Research Center on Aging.