‘Longevity Gene’ One Key to Long Life, Research

Milman agreed that CETP and HDL are far from the only factors in healthy aging and a long life. But understanding at least some of the genes behind longevity, and how they function, is important, she said.

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Cooking with Kathy Man

As ‘good’ cholesterol goes up, odds of heart disease, stroke go down.

Even among people who live well into their 90s, those with a particular gene variant may survive the longest, a new study finds.

The variant is in a gene known as CETP, and researchers have known for more than a decade that people who carry it have a better shot at an exceptionally long life — past 95 or even 100.

CETP is involved in cholesterol metabolism, and the longevity-linked variant raises blood levels of HDL cholesterol (the “good” kind) and promotes larger-than-normal HDL particles, researchers say.

The new findings show that even when you look at people who’ve already lived beyond age 95, those with the “favorable” CETP variant survive longer, said Dr. Sofiya Milman, an assistant professor at the Albert Einstein College of Medicine in New York City.

Milman was scheduled to present the findings Thursday…

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Filed under aging, cholesterol, Exercise, healthy living

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